Submarine　landslide　impact　is　a　threatening　load　in　the　service　lifecycles　of　deep-sea　pipelines　and　has　attracted　tremendous　attention　in　scientific　research　and　engineering　construction.　However,　no　effective　deep-sea　pipeline　protection　measures　are　applied　in　engineering　practice.　In　this　paper,　a　submarine　pipeline　with　honeycomb　holes　is　proposed.　This　pipeline　design　standard　is　quantified　by　defining　three　parameters.　Based　on　the　computational　fluid　dynamics　method,　numerical　calculations　of　common　circular　and　new　cross-section　pipelines　that　are　impacted　by　landslides　were　systematically　investigated　using　a　low-temperature　rheological　model.　The　results　demonstrate　that　the　higher　is　the　Reynolds　number,　the　larger　the　resistance　reduction　effect,　and　the　peak　drag　force　on　the　pipeline　with　honeycomb　holes　can　be　reduced　by　20%.　Simultaneously,　the　vibration　effect　of　the　pipeline　that　is　caused　by　the　lift　force　can　be　effectively　suppressed.　Further,　the　relevant　resistance　reduction　mechanisms　are　revealed　using　the　theories　of　boundary　layer　separation　and　turning　point　delay.　This　paper　proposes　a　preliminary　design　concept　of　a　submarine　pipeline　with　honeycomb　holes　that　effectually　reduces　the　impact　of　landslides,　sand　waves　and　bottom　currents　on　the　pipeline　to　protect　the　operational　safety.