A　tert-butyl　nitrite　(TBN)-mediated　synthesis　of　fluorinated　O-alkyloxime　ether　derivatives　with　bromodi-fluoroalkyl　reagents　as　the　fluorine　sources　has　been　developed.　A　variety　of　halodifluorinated　compounds　were　found　compatible,　delivering　the　desired　products　in　moderate　to　excellent　yields.　This　transformation　features　a　simple　operation,　can　be　done　in　air,　and　found　to　involve　radicals.　This　protocol　represents　a　straightforward　approach　to　access　various　fluorinated　O-alkyloxime　ether　derivatives.