In　this　work,　magnesium　silicate-based　sulfonated　polystyrene　sphere　composites　(SPS/MgSi)　were　synthesized　by　one-step　(SMD1)　and　two-step　(SMD2)　methods.　For　SMD1,　MgSi　particles　were　densely　assembled　on　the　surface　of　SPS,　assisted　by　complexation　between　Fe3+　and　hydroxyl　phenol.　For　SMD2,　SPS/SiO2　was　firstly　obtained　by　the　same　method　as　SMD1,　and　then　SPS/SiO2　was　transformed　directly　to　SPS/MgSi　under　hydrothermal　conditions.　Therefore,　MgSi　obtained　by　the　two-step　method　had　an　interwoven　structure.　Compared　to　SPS,　MgSi　and　SMD1,　SMD2　presented　a　larger　specific　surface　area　and　more　negative　surface　charges.　Therefore,　SMD2　showed　superior　adsorption　performance　toward　CIP　with　concentrations　of　5,　10　and　50　mg/L,　and　for　50　mg/L,　the　equilibrium　adsorption　capacity　could　reach　329.7　mg/g.　The　adsorption　process　is　fast　and　can　be　described　by　the　pseudo-second-order　kinetic　model.　The　relationship　between　pH　value　and　Zeta　potential　demonstrated　that　electrostatic　interaction　dominated　the　adsorption　process.　In　addition,　competitive　adsorption　showed　that　the　effect　of　Na+　was　negligible　but　the　effect　of　Ca2+　was　dependent　on　its　concentration.　Humid　acid　(HA)　could　slightly　promote　the　absorption　of　CIP　by　SMD2.　After　five　rounds　of　adsorption-desorption,　the　equilibrium　adsorption　capacity　of　SMD2　still　remained　at　288.6　mg/L　for　50　mg/L　CIP.　Notably,　SMD2　presented　likewise　superior　adsorption　capacity　for　CIP　with　concentrations　of　10　and　50　mg/L　in　Minjiang　source　water.　All　the　results　indicated　that　this　synthesis　method　is　universal　and　that　SMD2　has　potential　as　an　adsorbent　for　CIP　removal　from　aquatic　environments.　(C)　2020　Published　by　Elsevier　B.V.　on　behalf　of　The　Research　Centre　for　Eco-Environmental　Sciences,　Chinese　Academy　of　Sciences.