In　this　work,　magnesium　silicate-based　sulfonated　polystyrene　sphere　composites　(SPS/MgSi)　were　synthesized　by　one-step　(SMD1)　and　two-step　(SMD2)　methods.　For　SMD1,　MgSi　particles　were　densely　assembled　on　the　surface　of　SPS,　assisted　by　complexation　between　Fe3+　and　hydroxyl　phenol.　For　SMD2,　SPS/SiO2　was　firstly　obtained　by　the　same　method　as　SMD1,　and　then　SPS/SiO2　was　transformed　directly　to　SPS/MgSi　under　hydrothermal　conditions.　Therefore,　MgSi　obtained　by　the　two-step　method　had　an　interwoven　structure.　Compared　to　SPS,　MgSi　and　SMD1,　SMD2　presented　a　larger　specific　surface　area　and　more　negative　surface　charges.　Therefore,　SMD2　showed　superior　adsorption　performance　toward　CIP　with　concentrations　of　5,　10　and　50　mg/L,　and　for　50　mg/L,　the　equilibrium　adsorption　capacity　could　reach　329.7　mg/g.　The　adsorption　process　is　fast　and　can　be　described　by　the　pseudo-second-order　kinetic　model.　The　relationship　between　pH　value　and　Zeta　potential　demonstrated　that　electrostatic　interaction　dominated　the　adsorption　process.　In　addition,　competitive　adsorption　showed　that　the　effect　of　Na+　was　negligible　but　the　effect　of　Ca2+　was　dependent　on　its　concentration.　Humid　acid　(HA)　could　slightly　promote　the　absorption　of　CIP　by　SMD2.　After　five　rounds　of　adsorption-desorption,　the　equilibrium　adsorption　capacity　of　SMD2　still　remained　at　288.6　mg/L　for　50　mg/L　CIP.　Notably,　SMD2　presented　likewise　superior　adsorption　capacity　for　CIP　with　concentrations　of　10　and　50　mg/L　in　Minjiang　source　water.　All　the　results　indicated　that　this　synthesis　method　is　universal　and　that　SMD2　has　potential　as　an　adsorbent　for　CIP　removal　from　aquatic　environments.　©　2020