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学者姓名：黄立勤
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Cine imaging serves as a vital approach for non-invasive assessment of cardiac functional parameters. The imaging process of Cine cardiac MRI is inherently slow, necessitating the acquisition of data at multiple time points within each cardiac cycle to ensure adequate temporal resolution and motion information. Over prolonged data acquisition and during motion, Cine images can exhibit image degradation, leading to the occurrence of artifacts. Conventional image reconstruction methods often require expert knowledge for feature selection, which may result in information loss and suboptimal outcomes. In this paper, we employ a data-driven deep learning approach to address this issue. This approach utilizes supervised learning to compare data with different acceleration factors to full-sampled spatial domain data, training a context-aware network to reconstruct images with artifacts. In our model training strategy, we employ an adversarial approach to make the reconstructed images closer to ground truth. We incorporate loss functions based on adversarial principles and introduce image quality assessment as a constraint. Our context-aware model efficiently accomplishes artifact removal and image reconstruction tasks.
Keyword ：
Cine MRI Cine MRI Context Encoder Context Encoder Deep Learning Deep Learning Generative Adversarial Networks Generative Adversarial Networks Image Reconstruction Image Reconstruction
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| GB/T 7714 | Zhang, Weihua , Tang, Mengshi , Huang, Liqin et al. A Context-Encoders-Based Generative Adversarial Networks for Cine Magnetic Resonance Imaging Reconstruction [J]. | STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART. REGULAR AND CMRXRECON CHALLENGE PAPERS, STACOM 2023 , 2024 , 14507 : 359-368 . |
| MLA | Zhang, Weihua et al. "A Context-Encoders-Based Generative Adversarial Networks for Cine Magnetic Resonance Imaging Reconstruction" . | STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART. REGULAR AND CMRXRECON CHALLENGE PAPERS, STACOM 2023 14507 (2024) : 359-368 . |
| APA | Zhang, Weihua , Tang, Mengshi , Huang, Liqin , Li, Wei . A Context-Encoders-Based Generative Adversarial Networks for Cine Magnetic Resonance Imaging Reconstruction . | STATISTICAL ATLASES AND COMPUTATIONAL MODELS OF THE HEART. REGULAR AND CMRXRECON CHALLENGE PAPERS, STACOM 2023 , 2024 , 14507 , 359-368 . |
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Neural networks have found widespread application in medical image registration, although they typically assume access to the entire training dataset during training. In clinical scenarios, medical images of various anatomical targets, such as the heart, brain, and liver, may be obtained successively with advancements in imaging technologies and diagnostic procedures. The accuracy of registration on a new target may degrade over time, as the registration models become outdated due to domain shifts occurring at unpredictable intervals. In this study, we introduce a deep registration model based on continual learning to mitigate the issue of catastrophic forgetting during training with continuous data streams. To enable continuous network training, we propose a dynamic memory system based on a density-based clustering algorithm to retain representative samples from the data stream. Training the registration network on these representative samples enhances its generalization capabilities to accommodate new targets within the data stream. We evaluated our approach using the CHAOS dataset, which comprises multiple targets, such as the liver, left kidney, and spleen, to simulate a data stream. The experimental findings illustrate that the proposed continual registration network achieves comparable performance to a model trained with full data visibility.
Keyword ：
continual learning continual learning Data models Data models dynamic memory dynamic memory Heuristic algorithms Heuristic algorithms Liver Liver Medical diagnostic imaging Medical diagnostic imaging Registration network Registration network Streams Streams Task analysis Task analysis Training Training
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| GB/T 7714 | Ding, Wangbin , Sun, Haoran , Pei, Chenhao et al. Multi-Organ Registration With Continual Learning [J]. | IEEE SIGNAL PROCESSING LETTERS , 2024 , 31 : 1204-1208 . |
| MLA | Ding, Wangbin et al. "Multi-Organ Registration With Continual Learning" . | IEEE SIGNAL PROCESSING LETTERS 31 (2024) : 1204-1208 . |
| APA | Ding, Wangbin , Sun, Haoran , Pei, Chenhao , Jia, Dengqiang , Huang, Liqin . Multi-Organ Registration With Continual Learning . | IEEE SIGNAL PROCESSING LETTERS , 2024 , 31 , 1204-1208 . |
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Unsupervised domain adaptation(UDA) aims to mitigate the performance drop of models tested on the target domain, due to the domain shift from the target to sources. Most UDA segmentation methods focus on the scenario of solely single source domain. However, in practical situations data with gold standard could be available from multiple sources (domains), and the multi-source training data could provide more information for knowledge transfer. How to utilize them to achieve better domain adaptation yet remains to be further explored. This work investigates multi-source UDA and proposes a new framework for medical image segmentation. Firstly, we employ a multi-level adversarial learning scheme to adapt features at different levels between each of the source domains and the target, to improve the segmentation performance. Then, we propose a multi-model consistency loss to transfer the learned multi-source knowledge to the target domain simultaneously. Finally, we validated the proposed framework on two applications, i.e., multi-modality cardiac segmentation and cross-modality liver segmentation. The results showed our method delivered promising performance and compared favorably to state-of-the-art approaches. © 2023 IEEE.
Keyword ：
Job analysis Job analysis Knowledge management Knowledge management Medical imaging Medical imaging Semantics Semantics Semantic Segmentation Semantic Segmentation
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| GB/T 7714 | Pei, Chenhao , Wu, Fuping , Yang, Mingjing et al. Multi-Source Domain Adaptation for Medical Image Segmentation [J]. | IEEE Transactions on Medical Imaging , 2024 , 43 (4) : 1640-1651 . |
| MLA | Pei, Chenhao et al. "Multi-Source Domain Adaptation for Medical Image Segmentation" . | IEEE Transactions on Medical Imaging 43 . 4 (2024) : 1640-1651 . |
| APA | Pei, Chenhao , Wu, Fuping , Yang, Mingjing , Pan, Lin , Ding, Wangbin , Dong, Jinwei et al. Multi-Source Domain Adaptation for Medical Image Segmentation . | IEEE Transactions on Medical Imaging , 2024 , 43 (4) , 1640-1651 . |
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Gastric cancer is a serious malignant tumor. The gold standard for diagnosing gastric cancer is identifying cancer cells using pathological slides under microscopic examination. While many approaches have been proposed for gastric cancer segmentation, it is still difficult to train large-scale segmentation networks with scant gastroscopy data. Recently, Segmentation Anything Model (SAM) has received a lot of interest lately for its use in segmenting natural and medical images. However, due to high computational complexity and huge computational costs, the application of SAM in resource limited embedded medical devices is limited. In this paper, we proposed GC-SAM, a lightweight model for tumor segmentation. The prompt encoder and mask decoder have been fine-tuned to better face the challenge of segmenting pathological images of gastric cancer tissue. Evaluated on an internal dataset, the GC-SAM achieved state-of-the-art performance compared to classical image segmentation networks, with Dice coefficient of 0.8186. In addition, external validation has confirmed its superior generalization ability. This study demonstrates the great potential of adapting GC-SAM to pathological image segmentation tasks in gastric cancer tissue and provides the possibility for deep learning image segmentation to be transferred to embedded medical devices. © 2024 IEEE.
Keyword ：
External validation External validation Fine-tune Fine-tune Gastric cancer Gastric cancer Image segmentation Image segmentation Knowledge distillation Knowledge distillation SAM SAM
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| GB/T 7714 | Li, L. , Geng, Y. , Huang, L. et al. Segmentation of Gastric Cancer Pathological Slice Cancerous Region Based on Lightweight Improved SAM [未知]. |
| MLA | Li, L. et al. "Segmentation of Gastric Cancer Pathological Slice Cancerous Region Based on Lightweight Improved SAM" [未知]. |
| APA | Li, L. , Geng, Y. , Huang, L. , Li, J. , Niu, D. . Segmentation of Gastric Cancer Pathological Slice Cancerous Region Based on Lightweight Improved SAM [未知]. |
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Purpose: The identification of early-stage Parkinson's disease (PD) is important for the effective management of patients, affecting their treatment and prognosis. Recently, structural brain networks (SBNs) have been used to diagnose PD. However, how to mine abnormal patterns from high-dimensional SBNs has been a challenge due to the complex topology of the brain. Meanwhile, the existing prediction mechanisms of deep learning models are often complicated, and it is difficult to extract effective interpretations. In addition, most works only focus on the classification of imaging and ignore clinical scores in practical applications, which limits the ability of the model. Inspired by the regional modularity of SBNs, we adopted graph learning from the perspective of node clustering to construct an interpretable framework for PD classification.Methods: In this study, a multi-task graph structure learning framework based on node clustering (MNC-Net) is proposed for the early diagnosis of PD. Specifically, we modeled complex SBNs into modular graphs that facilitated the representation learning of abnormal patterns. Traditional graph neural networks are optimized through graph structure learning based on node clustering, which identifies potentially abnormal brain regions and reduces the impact of irrelevant noise. Furthermore, we employed a regression task to link clinical scores to disease classification, and incorporated latent domain information into model training through multi-task learning.Results: We validated the proposed approach on the Parkinsons Progression Markers Initiative dataset. Exper-imental results showed that our MNC-Net effectively separated the early-stage PD from healthy controls(HC) with an accuracy of 95.5%. The t-SNE figures have showed that our graph structure learning method can capture more efficient and discriminatory features. Furthermore, node clustering parameters were used as important weights to extract salient task-related brain regions(ROIs). These ROIs are involved in the development of mood disorders, tremors, imbalances and other symptoms, highlighting the importance of memory, language and mild motor function in early PD. In addition, statistical results from clinical scores confirmed that our model could capture abnormal connectivity that was significantly different between PD and HC. These results are consistent with previous studies, demonstrating the interpretability of our methods.
Keyword ：
Clinical scores Clinical scores Early Parkinson?s disease Early Parkinson?s disease Graph neural networks Graph neural networks Structural brain network Structural brain network
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| GB/T 7714 | Huang, Liqin , Ye, Xiaofang , Yang, Mingjing et al. MNC-Net: Multi-task graph structure learning based on node clustering for early Parkinson's disease diagnosis [J]. | COMPUTERS IN BIOLOGY AND MEDICINE , 2023 , 152 . |
| MLA | Huang, Liqin et al. "MNC-Net: Multi-task graph structure learning based on node clustering for early Parkinson's disease diagnosis" . | COMPUTERS IN BIOLOGY AND MEDICINE 152 (2023) . |
| APA | Huang, Liqin , Ye, Xiaofang , Yang, Mingjing , Pan, Lin , Zheng, Shao hua . MNC-Net: Multi-task graph structure learning based on node clustering for early Parkinson's disease diagnosis . | COMPUTERS IN BIOLOGY AND MEDICINE , 2023 , 152 . |
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Convolutions neural networks have obtained promising results in various medical image segmentation tasks. However, these methods ignore the problem of domain shift, which will lead to a model trained in a source domain performing poorly when applied to different target domains. In this work, we propose a two-stage segmentation network, and utilize histogram matching to eliminate domain shift. Specifically, the first stage obtains the region of interest by performing coarsely segmentation on down-sample images. Then the second stage segments the left atrium (LA) based on the region of interest. The method is evaluated on LAScarQS 2022 data-set, acquiring average Dice of 0.87790 for LA segmentation. Besides, the two-stage network is about four times faster against a single-stage network in the test phase. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
Keyword ：
Deep Learning Deep Learning Domain Shift Domain Shift Histogram Matching Augmentation Histogram Matching Augmentation Left Atrial Segmentation Left Atrial Segmentation
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| GB/T 7714 | Zhang, X. , Yang, X. , Huang, L. et al. Two Stage of Histogram Matching Augmentation for Domain Generalization: Application to Left Atrial Segmentation [未知]. |
| MLA | Zhang, X. et al. "Two Stage of Histogram Matching Augmentation for Domain Generalization: Application to Left Atrial Segmentation" [未知]. |
| APA | Zhang, X. , Yang, X. , Huang, L. , Huang, L. . Two Stage of Histogram Matching Augmentation for Domain Generalization: Application to Left Atrial Segmentation [未知]. |
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Automatic segmentation of left atrial (LA) scars from late gadolinium enhanced CMR images is a crucial step for atrial fibrillation (AF) recurrence analysis. However, delineating LA scars is tedious and error-prone due to the variation of scar shapes. In this work, we propose a boundary-aware LA scar segmentation network, which is composed of two branches to segment LA and LA scars, respectively. We explore the inherent spatial relationship between LA and LA scars. By introducing a Sobel fusion module between the two segmentation branches, the spatial information of LA boundaries can be propagated from the LA branch to the scar branch. Thus, LA scar segmentation can be performed condition on the LA boundaries regions. In our experiments, 40 labeled images were used to train the proposed network, and the remaining 20 labeled images were used for evaluation. The network achieved an average Dice score of 0.608 for LA scar segmentation. © 2023, The Author(s), under exclusive license to Springer Nature Switzerland AG.
Keyword ：
Boundary-Aware Boundary-Aware Left Atrial Scar Left Atrial Scar Multi-depth Segmentation Multi-depth Segmentation
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| GB/T 7714 | Wu, M. , Ding, W. , Yang, M. et al. Multi-depth Boundary-Aware Left Atrial Scar Segmentation Network [未知]. |
| MLA | Wu, M. et al. "Multi-depth Boundary-Aware Left Atrial Scar Segmentation Network" [未知]. |
| APA | Wu, M. , Ding, W. , Yang, M. , Huang, L. . Multi-depth Boundary-Aware Left Atrial Scar Segmentation Network [未知]. |
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从高分辨遥感图像中快速提取道路信息在地图绘制、城市规划和更新GIS数据库等方面至关重要，半自动道路提取作为道路测绘内业的主要方式，是一项劳动密集型工作。为了降低人工介入代价，提高工作效率，本文提出了一种基于测地距离场的道路中心线快速提取算法。首先，利用最佳圆形模板算法，自动估计道路宽度的同时将人工种子调整到道路中心；然后，为了定位道路中心线，提出基于道路显著图的柔性道路中心核密度估计算法，克服了传统道路中心核密度估计中道路分割阈值预设困难的问题；本文提出快速生成测地距离场算法，可快速跟踪种子之间的测地线，大大提高了道路中心线提取的效率；最后对测地线坐标进行均值滤波平滑，获得了光滑的道路中心线。大量的试验和对比数据表明，本文算法能够在保证精度的前提下快速提取道路中心线，大幅降低人工介入代价，提高道路提取的工作效率；值得强调的是，本文算法在图像分辨率固定的前提下，提取任意长度道路中心线的耗时近乎相同，且无须设置超参数，具有较好的人机交互体验。
Keyword ：
曲线平滑 曲线平滑 测地距离场 测地距离场 道路中心线提取 道路中心线提取 遥感图像 遥感图像
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| GB/T 7714 | 连仁包 , 张振敏 , 廖一鹏 et al. 结合测地距离场与曲线平滑的遥感图像道路中心线快速提取 [J]. | 测绘学报 , 2023 , 52 (08) : 1317-1329 . |
| MLA | 连仁包 et al. "结合测地距离场与曲线平滑的遥感图像道路中心线快速提取" . | 测绘学报 52 . 08 (2023) : 1317-1329 . |
| APA | 连仁包 , 张振敏 , 廖一鹏 , 邹长忠 , 黄立勤 . 结合测地距离场与曲线平滑的遥感图像道路中心线快速提取 . | 测绘学报 , 2023 , 52 (08) , 1317-1329 . |
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Multi-modality cardiac imaging plays a key role in the management of patients with cardiovascular diseases. It allows a combination of complementary anatomical, morphological and functional information, increases diagnosis accuracy, and improves the efficacy of cardiovascular interventions and clinical outcomes. Fully automated processing and quantitative analysis of multi-modality cardiac images could have a direct impact on clinical research and evidence-based patient management. However, these require overcoming significant challenges including inter-modality misalignment and finding optimal methods to integrate information from different modalities. This paper aims to provide a comprehensive review of multi-modality imaging in cardiology, the computing methods, the validation strategies, the related clinical workflows and future perspectives. For the computing methodologies, we have a favored focus on the three tasks, i.e., registration, fusion and segmentation, which generally involve multi-modality imaging data, either combining information from different modalities or transferring information across modalities. The review highlights that multi-modality cardiac imaging data has the potential of wide applicability in the clinic, such as trans-aortic valve implantation guidance, myocardial viability assessment, and catheter ablation therapy and its patient selection. Nevertheless, many challenges remain unsolved, such as missing modality, modality selection, combination of imaging and non-imaging data, and uniform analysis and representation of different modalities. There is also work to do in defining how the well-developed techniques fit in clinical workflows and how much additional and relevant information they introduce. These problems are likely to continue to be an active field of research and the questions to be answered in the future.
Keyword ：
Cardiac Cardiac Fusion Fusion Multi-modality imaging Multi-modality imaging Registration Registration Review Review Segmentation Segmentation
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| GB/T 7714 | Li, Lei , Ding, Wangbin , Huang, Liqin et al. Survey paper Multi-modality cardiac image computing: A survey [J]. | MEDICAL IMAGE ANALYSIS , 2023 , 88 . |
| MLA | Li, Lei et al. "Survey paper Multi-modality cardiac image computing: A survey" . | MEDICAL IMAGE ANALYSIS 88 (2023) . |
| APA | Li, Lei , Ding, Wangbin , Huang, Liqin , Zhuang, Xiahai , Grau, Vicente . Survey paper Multi-modality cardiac image computing: A survey . | MEDICAL IMAGE ANALYSIS , 2023 , 88 . |
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针对基于传统非刚性医学图像配准的心脏超声序列图像配准方法缺乏自动性及配准速度慢、准确率较低的问题,将基于深度学习的医学图像配准算法应用于心脏超声序列图像配准,通过引入通道注意力机制,构建由注意力机制模块、Unet卷积神经网络模块及空间转换模块STN构成的配准模型.实验选取不同的相似性损失函数和平滑损失函数,对比VoxelMorph配准模型,相关配准性能指标都有不同程度的改进,DICE指标提升0.42％,MI指标提升2.5％,SSIM提升3.7％,NRMSE减小9％,表明配准模型的有效性.从配准效果及配准时间分析,配准模型基本可以满足心脏超声序列图像配准的实时性需求,具有一定的临床应用价值.
Keyword ：
Unet卷积神经网络 Unet卷积神经网络 医学图像配准 医学图像配准 心脏超声序列图像 心脏超声序列图像 深度学习 深度学习 通道注意力 通道注意力
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| GB/T 7714 | 兰其斌 , 黄立勤 . 基于注意力机制无监督心脏超声序列图像配准 [J]. | 福州大学学报（自然科学版） , 2023 , 51 (1) : 41-48 . |
| MLA | 兰其斌 et al. "基于注意力机制无监督心脏超声序列图像配准" . | 福州大学学报（自然科学版） 51 . 1 (2023) : 41-48 . |
| APA | 兰其斌 , 黄立勤 . 基于注意力机制无监督心脏超声序列图像配准 . | 福州大学学报（自然科学版） , 2023 , 51 (1) , 41-48 . |
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