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学者姓名：刘树滔
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Abstract ：
为探讨冷萃咖啡的抗氧化特性及其在中医经络理论中的归经属性,文章通过氧化还原电位(ORP)测定、铁离子还原能力(FRAP)测试以及 1,1-二苯基-2-三硝基苯肼(DPPH)自由基清除活性检测来评估其抗氧化性,同时,采用经络体表电位测量方法来确定其对特定经络的影响.研究结果显示:冷萃咖啡显示出一定程度的还原性和抗氧化能力,具体表现为Δ ORP值为(-70.3±6.0)mV,FRAP值为(0.49±0.03)mmol/L FeSO4,然而在DPPH自由基清除方面未表现出明显效果;饮用后发现人体心经、心包经及肺经的电压显著增加,分别为 13.8 mV(P＜0.05)、12.9 mV和 6.3 mV(P＜0.05),而脾经、肝经与肾经则未见变化.结论:适量摄入冷萃咖啡可能有助于增强某些关键经络的功能活动,特别是那些与心脏健康密切相关的心经、心包经和肺经.这项研究为理解传统饮品如冷萃咖啡如何影响人体提供了新的视角,也为开发具有特定健康益处的产品开辟了可能性.
Keyword ：
冷萃咖啡 冷萃咖啡 心包经 心包经 心经 心经 抗氧化性 抗氧化性 经络归经属性 经络归经属性
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| GB/T 7714 | 郭静科 , 陆志伟 , 司凡 et al. 冷萃咖啡抗氧化性与经络归经属性的初步探究 [J]. | 福建轻纺 , 2025 , (4) : 33-37 . |
| MLA | 郭静科 et al. "冷萃咖啡抗氧化性与经络归经属性的初步探究" . | 福建轻纺 4 (2025) : 33-37 . |
| APA | 郭静科 , 陆志伟 , 司凡 , 刘树滔 , 饶平凡 , 山云辉 . 冷萃咖啡抗氧化性与经络归经属性的初步探究 . | 福建轻纺 , 2025 , (4) , 33-37 . |
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To explore the formation pattern of 5-hydroxymethylfurfural (5-HMF) and the safety of dried longan during processing and storage, this study monitored the changes in 5-HMF content during drying and storage at different temperatures. The changes in the contents of reducing sugar, total acid and total free amino acid and browning degree during processing were determined and their correlation with 5-HMF content was analyzed. Moreover, the safety of dried longan was analyzed using in vitro simulated digestion experiments and a Caco-2 cell model. The results showed that as the drying temperature increased above 85 ℃, the 5-HMF content significantly increased (P © 2024 Chinese Chamber of Commerce. All rights reserved.
Keyword ：
Drying Drying
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| GB/T 7714 | Fang, Ronghui , Sang, Wanjing , Cheng, Qun et al. Effects of Drying, Storage Conditions and Simulated Digestion on the Content of 5-Hydroxymethylfurfural in Dried Longan [J]. | Food Science , 2024 , 45 (19) : 41-48 . |
| MLA | Fang, Ronghui et al. "Effects of Drying, Storage Conditions and Simulated Digestion on the Content of 5-Hydroxymethylfurfural in Dried Longan" . | Food Science 45 . 19 (2024) : 41-48 . |
| APA | Fang, Ronghui , Sang, Wanjing , Cheng, Qun , Liu, Shutao . Effects of Drying, Storage Conditions and Simulated Digestion on the Content of 5-Hydroxymethylfurfural in Dried Longan . | Food Science , 2024 , 45 (19) , 41-48 . |
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为探究龙眼干在加工、储存过程中5-羟甲基糠醛(5-hydroxymethylfurfural,5-HMF)的生成规律及安全性,测定不同温度干制、储存过程中龙眼干5-HMF含量的变化,以及干制过程中还原糖、总酸、总游离氨基酸和褐变度的变化,并分析各种变化之间的相关性;然后通过体外模拟消化实验及肠道上皮细胞模型对其进行安全性分析.结果表明:随着干制温度的上升,5-HMF在干制温度大于85 ℃时显著升高(P＜0.05),5-HMF含量与总酸含量和褐变度呈正相关,与总游离氨基酸及还原糖含量呈负相关;龙眼干在冷藏(4 ℃)、常温(25 ℃)、高温(37 ℃)储存条件下,5-HMF随储存时间延长先上升后下降,不同条件下的增长趋势不同,其中25 ℃条件下最快开始下降且总体含量较低;龙眼干中的5-HMF含量在口腔消化阶段短暂升高,在胃、肠消化阶段显著降低;龙眼干水提液能抑制5-HMF的吸收,且对于24 mmol/L 5-HMF的Caco-2细胞毒性有一定的抵消作用.结果说明,优化龙眼干的干制和储存条件能够降低5-HMF的含量;正常食用的情况下,人体消化道能降低龙眼干中5-HMF,提高其食用安全性.
Keyword ：
5-羟甲基糠醛 5-羟甲基糠醛 安全性 安全性 美拉德反应 美拉德反应 龙眼干 龙眼干
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| GB/T 7714 | 方榕辉 , 桑婉婧 , 程群 et al. 干制、储存条件及模拟消化对龙眼干中5-羟甲基糠醛含量的影响 [J]. | 食品科学 , 2024 , 45 (19) : 41-48 . |
| MLA | 方榕辉 et al. "干制、储存条件及模拟消化对龙眼干中5-羟甲基糠醛含量的影响" . | 食品科学 45 . 19 (2024) : 41-48 . |
| APA | 方榕辉 , 桑婉婧 , 程群 , 刘树滔 . 干制、储存条件及模拟消化对龙眼干中5-羟甲基糠醛含量的影响 . | 食品科学 , 2024 , 45 (19) , 41-48 . |
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Oxidative stress is generally considered inseparable from the development and exacerbation of ulcerative colitis (UC). Therefore, reducing oxidative stress has become a possible way to alleviate UC. In this study, the therapeutic effects of different doses of liposome-embedded superoxide dismutase (L-SOD) on mice with DSS-induced UC were systematically investigated. The results showed that L-SOD significantly attenuated the signs of colitis in mice, including colonic shortening, diarrhoea, bloody stools, and histopathological changes. L-SOD ameliorated DSS-induced oxidative damage, increased SOD, catalase (CAT), and glutathione (GSH) activities, and decreased malondialdehyde (MDA) levels. In addition, L-SOD ameliorated the inflammatory response by inhibiting the expression of myeloperoxidase (MPO) and pro-inflammatory cytokines and protected barrier function by promoting the expression of the tight junction proteins occludin and ZO-1 in the colon. Importantly, the results demonstrated a bell-shaped distribution of therapeutic effects relative to the administered dose, with an optimal dose of 150 000 U kg(-1). These results indicate that L-SOD has great potential as an ingredient in functional foods for the prevention and mitigation of UC.
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| GB/T 7714 | Zhang, Chi , Hu, Yujia , Yuan, Yi et al. Liposome-embedded SOD attenuated DSS-induced ulcerative colitis in mice by ameliorating oxidative stress and intestinal barrier dysfunction [J]. | FOOD & FUNCTION , 2023 , 14 (9) : 4392-4405 . |
| MLA | Zhang, Chi et al. "Liposome-embedded SOD attenuated DSS-induced ulcerative colitis in mice by ameliorating oxidative stress and intestinal barrier dysfunction" . | FOOD & FUNCTION 14 . 9 (2023) : 4392-4405 . |
| APA | Zhang, Chi , Hu, Yujia , Yuan, Yi , Guo, Jingke , Li, Henian , Li, Qiaoling et al. Liposome-embedded SOD attenuated DSS-induced ulcerative colitis in mice by ameliorating oxidative stress and intestinal barrier dysfunction . | FOOD & FUNCTION , 2023 , 14 (9) , 4392-4405 . |
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The chitosan-coated alginate gel particles (CS/SA) and chitosan-coated alginate-shellac gel particles (CS/SA/Lac) were constructed to serve as a potential oral delivery system to enhance the stability and activity of superoxide dismutase (SOD) in this study. The encapsulation efficiency (EE), enzyme activity retention ratio (ER), particle structure, and SOD release behavior, as well as the effect of shellac, were evaluated. The best formula is determined by the percentage of total effective activity (PTEA).The results showed that CS/SA prepared by 0.30 parts per thousand chitosan, 1.00% CaCl2, 2.00% sodium alginate (M/G = 1:1, Mw: 38,857 kDa), and gelation solution pH 5.50 had the best chitosan shell, the strongest gel structure and the maximum PTEA which was 10.75 +/- 1.45%. Based on the optimal formula, addition of shellac that formed shellac-Ca2+ microspheres in the gel network was averse to SOD encapsulation, but it significantly improved the stability of SOD in gastric conditions. By adding 15.00% shellac, the PTEA reached 16.30 +/- 1.64%. At optimal formulation, SOD encapsulated in CS/SA was completely released in the stimulated intestinal fluid and accumulative release enzyme activity (EA) was 966.62 +/- 103.75 (U) after 6 h. However, the CS/SA/Lac with a low swelling ratio only released SOD in stimulated colonic fluid and the EA value reached 1692.28 +/- 101.82 (U) after 1 h. These findings demonstrated that CS/SA and CS/SA/Lac were excellent candidates for SOD oral administration, which was useful in the food and biomedical industries for developing functional products containing SOD.
Keyword ：
Chitosan-coated alginate Chitosan-coated alginate Chitosan-coated alginate gel particles Chitosan-coated alginate gel particles Intestinal delivery Intestinal delivery shellac gel particles shellac gel particles Superoxide dismutase Superoxide dismutase
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| GB/T 7714 | Zhu, Zeliang , Yuan, Yi , Guo, Jingke et al. Encapsulation of SOD in chitosan-coated gel particles of alginate or mixture of alginate and shellac for targeted intestinal delivery [J]. | FOOD HYDROCOLLOIDS , 2023 , 142 . |
| MLA | Zhu, Zeliang et al. "Encapsulation of SOD in chitosan-coated gel particles of alginate or mixture of alginate and shellac for targeted intestinal delivery" . | FOOD HYDROCOLLOIDS 142 (2023) . |
| APA | Zhu, Zeliang , Yuan, Yi , Guo, Jingke , Luo, Xiaolin , Liu, Shutao , Miao, Song . Encapsulation of SOD in chitosan-coated gel particles of alginate or mixture of alginate and shellac for targeted intestinal delivery . | FOOD HYDROCOLLOIDS , 2023 , 142 . |
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With an increasing incidence rate,ulcerative colitis (UC) is an idiopathic inflammation of the colon causing diarrhea and blood in the stool. Existing studies have shown that oxidative stress is an important factor leading to UC, while superoxide dismutase (SOD) has a certain effect on relieving UC symptoms. To improve its bioavailability, superoxide dismutase (SOD) was self-assembled into nanoparticles (ΔSOD) by heating it. The activity, transmembrane capacity and radical scavenging capacity of ΔSOD were significantly better than those of native SOD. ΔSOD liposomes (L-ΔSOD) were prepared by reverse-phase evaporation and orally administered to mice with UC. The results showed that compared with the positive control and model groups, L-ΔSOD significantly ameliorated UC, reduced disease activity index (DAI) score, restored the morphology of colon tissue, increased the length of colon, reduced the density of colon and spleen coefficient, and restored the integrity of mucosal epithelium. Besides, L-ΔSOD could reduce the contents of malondialdehyde (MDA) and pro-inflammatory factors in colon tissue and increase the levels of glutathione peroxidase (GSH-Px) and tight junction protein mRNA expression. These results confirmed that oral L-ΔSOD has a good ameliorative effect on UC, which will lay the foundation for the application of SOD in promoting human health. © 2023, China Food Publishing Company. All right reserved.
Keyword ：
Antioxidants Antioxidants Biochemistry Biochemistry Disease control Disease control Diseases Diseases Liposomes Liposomes Mammals Mammals Nanoparticles Nanoparticles Restoration Restoration Superoxide dismutase Superoxide dismutase Tissue Tissue
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| GB/T 7714 | Li, Qiaoling , Li, Henian , Guo, Jingke et al. Ameliorative Effect of Orally Administered Nano-Superoxide Dismutase Liposomes on Ulcerative Colitis in Mice [J]. | Food Science , 2023 , 44 (1) : 166-174 . |
| MLA | Li, Qiaoling et al. "Ameliorative Effect of Orally Administered Nano-Superoxide Dismutase Liposomes on Ulcerative Colitis in Mice" . | Food Science 44 . 1 (2023) : 166-174 . |
| APA | Li, Qiaoling , Li, Henian , Guo, Jingke , Zhu, Zeliang , Teng, Wei , Hu, Yujia et al. Ameliorative Effect of Orally Administered Nano-Superoxide Dismutase Liposomes on Ulcerative Colitis in Mice . | Food Science , 2023 , 44 (1) , 166-174 . |
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溃疡性结肠炎(ulcerative colitis,UC)是一种特发性结肠炎症,会引起腹泻、便血、腹痛等症状,其发病率不断上升.现有研究表明氧化应激是造成UC的重要原因之一,而超氧化物歧化酶(superoxide dismutase,SOD)在缓解UC症状上有一定的效果.因此,本实验通过加热SOD使其自组装形成SOD纳米颗粒(记作ΔSOD),以提高SOD的生物利用度,通过理化指标分析发现ΔSOD纳米颗粒的活力、细胞跨膜能力以及自由基清除能力较天然SOD均显著提高;再采用逆向蒸发法制备ΔSOD脂质体(记作L-ΔSOD),并灌胃UC模型小鼠,结果显示,与阳性对照组和模型组相比,L-ΔSOD可以显著改善UC,降低小鼠疾病活动指数评分,恢复小鼠结肠组织状态,增加结肠长度,降低结肠密度和脾脏系数,恢复黏膜上皮完整性;同时L-ΔSOD可以降低结肠组织MDA含量,并通过减少细胞促炎因子质量浓度、提高谷胱甘肽过氧化物酶活力和紧密连接蛋白mRNA水平来改善UC.综上,L-ΔSOD对UC具有较好的改善作用,本实验可为SOD促进人体健康的实际应用提供参考.
Keyword ：
抗氧化 抗氧化 溃疡性结肠炎 溃疡性结肠炎 纳米颗粒 纳米颗粒 脂质体 脂质体 超氧化物歧化酶 超氧化物歧化酶
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| GB/T 7714 | 黎俏灵 , 李鹤年 , 郭静科 et al. 灌胃纳米超氧化物歧化酶脂质体对小鼠溃疡性结肠炎的改善作用 [J]. | 食品科学 , 2023 , 44 (1) : 166-174 . |
| MLA | 黎俏灵 et al. "灌胃纳米超氧化物歧化酶脂质体对小鼠溃疡性结肠炎的改善作用" . | 食品科学 44 . 1 (2023) : 166-174 . |
| APA | 黎俏灵 , 李鹤年 , 郭静科 , 朱则亮 , 滕薇 , 胡雨嘉 et al. 灌胃纳米超氧化物歧化酶脂质体对小鼠溃疡性结肠炎的改善作用 . | 食品科学 , 2023 , 44 (1) , 166-174 . |
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A novel pre-aggregation process prior to gelation was applied to modulate the aggregation and gelation pathway of soy protein isolate (SPI). SPI dispersions were pre-aggregated with CaSO4, MgSO4 or ZnSO4 at 0-15 mM and then gelled by adding CaSO4 up to a final salt concentration of 35 mM. Compared with the sample without preaggregation, the storage modulus of SPI gels pre-aggregated with 10 mM CaSO4, 10 mM MgSO4, and 2.5 mM ZnSO4 were increased by 50.5%, 35.7%, and 63.6%, respectively. The fracture stress, texture profile analysis parameters, and water holding capacity were markedly improved by an appropriate level of pre-aggregation. To a certain extent, pre-aggregation could promote the formation of uniform structure with thicker strands, whereas over-aggregation resulted in a coarser network, which was correlated with the volume-mean diameter (D4,3) of pre-aggregated SPI particles. The results are of great value for further understanding of gelation mechanism of proteins.
Keyword ：
Gel Gel Microstructure Microstructure Pre-aggregation Pre-aggregation Rheological property Rheological property Soy protein isolate Soy protein isolate Textural property Textural property
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| GB/T 7714 | Wang, Xufeng , Yu, Mengqin , Wang, Zhenzhong et al. Modulation of soy protein isolate gel properties by a novel "two-step" gelation process: Effects of pre-aggregation with different divalent sulfates [J]. | FOOD CHEMISTRY , 2022 , 394 . |
| MLA | Wang, Xufeng et al. "Modulation of soy protein isolate gel properties by a novel "two-step" gelation process: Effects of pre-aggregation with different divalent sulfates" . | FOOD CHEMISTRY 394 (2022) . |
| APA | Wang, Xufeng , Yu, Mengqin , Wang, Zhenzhong , Luo, Kaiyun , Adhikari, Benu , Miao, Song et al. Modulation of soy protein isolate gel properties by a novel "two-step" gelation process: Effects of pre-aggregation with different divalent sulfates . | FOOD CHEMISTRY , 2022 , 394 . |
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Superoxide dismutase (SOD) is an enzyme found in most food sources, might be a candidate to reduce oxidative damage to intestinal barrier, thereby ameliorating the vicious circle between hyperglycemia and the oxidative damage. Here we report the oral administration of SOD, liposome-embedded SOD (L-SOD), and SOD hydrolysate to type 2 diabetic model rats to confirm this hypothesis. Oxidative damage severity in model rat intestine was indicated by malondialdehyde level, GSSG/GSH ratio, and antioxidant enzyme activity. The damage was significantly repaired by L-SOD. Furthermore, blood glucose and related indexes correlated well not only with oxidative damage results but also with indexes indicating physical intestinal damage such as colon density, H&E staining, immunohistochemical analysis of the tight junction proteins occludin and ZO-1 in the colon, as well as lipopolysaccharide and related inflammatory cytokine levels. The order of the magnitude of the effects of these SOD preparations was L-SOD > SOD > SOD hydrolysate. These data indicate that orally administered SOD can exhibit glucose-lowering effect via targeting the intestine of diabetic rats and systemic lipopolysaccharide influx.
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| GB/T 7714 | Guo, Jingke , Liu, Hangqi , Zhao, Dan et al. Glucose-lowering effects of orally administered superoxide dismutase in type 2 diabetic model rats [J]. | NPJ SCIENCE OF FOOD , 2022 , 6 (1) . |
| MLA | Guo, Jingke et al. "Glucose-lowering effects of orally administered superoxide dismutase in type 2 diabetic model rats" . | NPJ SCIENCE OF FOOD 6 . 1 (2022) . |
| APA | Guo, Jingke , Liu, Hangqi , Zhao, Dan , Pan, Chaoyi , Jin, Xuepu , Hu, Yujia et al. Glucose-lowering effects of orally administered superoxide dismutase in type 2 diabetic model rats . | NPJ SCIENCE OF FOOD , 2022 , 6 (1) . |
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为了改善大豆分离蛋白(soy protein isolate, SPI)凝胶品质,提出了一种两步制备凝胶的新方法:首先利用3种不同浓度(0～15 mmol/L)的硫酸盐(CaSO_4、MgSO_4和ZnSO_4)对SPI进行预聚集处理,然后通过添加CaSO_4至盐离子总浓度为35 mmol/L使蛋白质凝胶化,并探讨了不同盐离子预聚集对SPI结构及凝胶特性的影响。结果表明:盐离子与蛋白质分子之间的相互作用是自发的吸热反应,由熵变驱动,滴定ZnSO_4引起的热量变化较CaSO_4和MgSO_4更为剧烈;盐离子的加入引起了SPIα-螺旋结构含量上升,β-折叠结构含量下降及荧光强度降低。在同一浓度条件...
Keyword ：
凝胶性 凝胶性 大豆分离蛋白 大豆分离蛋白 盐离子 盐离子 相互作用 相互作用 预聚集 预聚集
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| GB/T 7714 | 王旭峰 , 于梦勤 , 王振忠 et al. 基于两步法研究盐离子预聚集对大豆分离蛋白凝胶性的影响 [J]. | 食品科学技术学报 , 2022 , 40 (01) : 65-75 . |
| MLA | 王旭峰 et al. "基于两步法研究盐离子预聚集对大豆分离蛋白凝胶性的影响" . | 食品科学技术学报 40 . 01 (2022) : 65-75 . |
| APA | 王旭峰 , 于梦勤 , 王振忠 , 罗凯云 , 刘树滔 . 基于两步法研究盐离子预聚集对大豆分离蛋白凝胶性的影响 . | 食品科学技术学报 , 2022 , 40 (01) , 65-75 . |
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