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学者姓名：魏发南
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Abstract ：
The field of bioelectronics has witnessed significant advancements, offering practical solutions for personalized healthcare through the acquisition and analysis of skin-based physical, chemical, and electrophysiological signals. Despite these advancements, current bioelectronics face several challenges, including complex preparation procedures, poor skin adherence, susceptibility to motion artifacts, and limited personalization and reconfigurability capabilities. In this study, we introduce an innovative method for fabricating erasable bioelectronics on a flexible substrate coating adhered to the skin using a ballpoint pen without any postprocessing. Our approach yields devices that are thin, erasable, reconfigurable, dry-friction resistant, self-healing, and highly customizable. We demonstrate the multifunctionality of these on-skin bioelectronics through their application as strain sensors for motion monitoring, temperature and humidity sensors for breath monitoring, and heating elements for target point hyperthermia. The potential of our bioelectronics in personalized medicine is substantial, particularly in health monitoring. We provide a novel solution for achieving efficient and convenient personalized medical services, addressing the limitations of existing technologies and paving the way for next-generation wearable health devices.
Keyword ：
bioelectronics bioelectronics direct writing direct writing erasable erasable multifunctional multifunctional on-skin on-skin
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| GB/T 7714 | Zhu, Xintao , Liu, Wei , Luo, Qinzhou et al. Erasable and Multifunctional On-Skin Bioelectronics Prepared by Direct Writing [J]. | ACS SENSORS , 2025 , 10 (4) : 2850-2860 . |
| MLA | Zhu, Xintao et al. "Erasable and Multifunctional On-Skin Bioelectronics Prepared by Direct Writing" . | ACS SENSORS 10 . 4 (2025) : 2850-2860 . |
| APA | Zhu, Xintao , Liu, Wei , Luo, Qinzhou , Lv, Zhen , Yao, Ligang , Wei, Fanan . Erasable and Multifunctional On-Skin Bioelectronics Prepared by Direct Writing . | ACS SENSORS , 2025 , 10 (4) , 2850-2860 . |
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In recent years, continuum soft robots have emerged as a promising avenue for the advancement of in vivo therapeutic interventions. However, the current continuum robots are often limited to singular functionalities and exhibit a deficiency in diagnostic capabilities for vascular lesions. For example, vasculitis often leads to temperature abnormalities in local blood vessels, and the existing continuum robots are unable to accurately detect the lesion area based on this characteristic. To address this issue, this paper presents the design of a multifunctional integrated thermally drawn polymer multichannel continuum robot. First, the magnetic deformation of the continuum robot was theoretically analyzed, and the robot's locomotion within a flow field was experimentally verified. Moreover, different channels of the multichannel continuum robot were independently designed for specific functions, enabling multithreaded operations. It can perform real-time sensing and monitoring of external environmental temperatures with high resolution and carry out targeted drug delivery as well as neural electrical stimulation. We successfully conducted in vitro experiments on isolated frog sciatic nerves, confirming the effectiveness of the multichannel continuum robot for biological treatment. The multichannel continuum robot shows great potential in the diagnosis and treatment of vasculitis in situ and nerve system disorder.
Keyword ：
continuum soft robot continuum soft robot electrical nerve stimulation electrical nerve stimulation magneticresponse magneticresponse multifunction multifunction temperaturemonitoring temperaturemonitoring
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| GB/T 7714 | Liu, Wei , Luo, Qinzhou , Zhu, Xintao et al. A Multichannel Continuum Robot for In Situ Diagnosis and Treatment of Vascular Lesions [J]. | ACS BIOMATERIALS SCIENCE & ENGINEERING , 2025 , 11 (5) : 3071-3081 . |
| MLA | Liu, Wei et al. "A Multichannel Continuum Robot for In Situ Diagnosis and Treatment of Vascular Lesions" . | ACS BIOMATERIALS SCIENCE & ENGINEERING 11 . 5 (2025) : 3071-3081 . |
| APA | Liu, Wei , Luo, Qinzhou , Zhu, Xintao , Liu, Ming , Yao, Ligang , Wei, Fanan . A Multichannel Continuum Robot for In Situ Diagnosis and Treatment of Vascular Lesions . | ACS BIOMATERIALS SCIENCE & ENGINEERING , 2025 , 11 (5) , 3071-3081 . |
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Abstract ：
Abdominal and intrauterine adhesions are common postoperative problems that can cause serious complications. Current adhesives are usually double sided and suffer from poor wet adhesion, nondegradability, and monofunctionality, which limits their application in preventing postoperative adhesions. Herein, a bioinspired microstructured Janus bioadhesive, named OD/GM@PG, with a wet adhesive inner layer and an antiadhesive outer layer is prepared by combining electrostatic spun and adhesive materials. By using both capillary suction and a catechol-based strategy, the wet adhesive strength and interfacial toughness of the Janus bioadhesive reach 98 kPa and 325 J m-2, respectively, which are much higher than those of commercial fibrin glues and cyanoacrylate glues. The electrostatic spun outer layer acts as a physical barrier with antiadhesive and friction-reducing effects. Additionally, the Janus bioadhesive demonstrates biodegradable, hemostatic, antioxidative, anti-inflammatory, and prohealing properties. In vivo results show that the asymmetric adhesion effect of the Janus bioadhesive effectively preventing postoperative abdominal and intrauterine adhesions. Notably, tandem mass tags-labeled quantitative proteomics analysis demonstrate that the expression of inflammatory response-associated proteins (S100A8, S100A9) is associated with adhesion; the Janus bioadhesive significantly downregulates this expression. Therefore, the OD/GM@PG Janus bioadhesive is a promising candidate for preventing postoperative adhesions. A bioinspired microstructured Janus bioadhesive with an asymmetric structure and adhesion behavior is prepared by combining electrostatic spinning and adhesive materials. By employing capillary suction and a catechol-based strategy, the Janus bioadhesive exhibits impressive wet adhesive strength and interfacial toughness. Furthermore, the asymmetric adhesion effect of the Janus bioadhesive effectively alleviates postoperative abdominal and intrauterine adhesions. image
Keyword ：
capillary suction capillary suction fertility restoration fertility restoration Janus bioadhesive Janus bioadhesive preventing postoperative adhesion preventing postoperative adhesion wet adhesion wet adhesion
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| GB/T 7714 | Lv, Yicheng , Cai, Fengying , Zhao, Xingkai et al. Bioinspired Microstructured Janus Bioadhesive for the Prevention of Abdominal and Intrauterine Adhesions [J]. | ADVANCED FUNCTIONAL MATERIALS , 2024 , 34 (21) . |
| MLA | Lv, Yicheng et al. "Bioinspired Microstructured Janus Bioadhesive for the Prevention of Abdominal and Intrauterine Adhesions" . | ADVANCED FUNCTIONAL MATERIALS 34 . 21 (2024) . |
| APA | Lv, Yicheng , Cai, Fengying , Zhao, Xingkai , Zhu, Xintao , Wei, Fanan , Zheng, Yunquan et al. Bioinspired Microstructured Janus Bioadhesive for the Prevention of Abdominal and Intrauterine Adhesions . | ADVANCED FUNCTIONAL MATERIALS , 2024 , 34 (21) . |
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The traditional pneumatic soft actuator offers significant advantages, including high output force and strong deformation capabilities, making it widely utilized in soft robotics. Building on this foundation, a phase change drive mechanism addresses the size and weight issues associated with pneumatic actuators, but it also results in prolonged working times. In this paper, we propose a method for manufacturing a chamber using PVA 3D printing and design an electrothermal soft actuator featuring a double multichamber structure driven by the principles of phase change. The actuator utilizes phase transformation to generate air pressure, which enhances the recovery speed and expands the working range through the antagonistic effect. Under low voltage (<8 V), the average deformation rate of the actuator designed in this paper is increased by more than 50% through the antagonistic effect of the double multicavity structure, which effectively improves the actuator's overall efficiency. In addition, the actuator can achieve a unilateral deformation of 18.7 mm and generate a load output force of 540.7 g while weighing only 15.8 g.
Keyword ：
Antagonistic effect Antagonistic effect Double multichamber Double multichamber Electrothermal Electrothermal Phase change Phase change Pneumatic actuator Pneumatic actuator Softactuator Softactuator
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| GB/T 7714 | Wei, Fanan , Yang, Lingyun , Lv, Zhen et al. Response Speed of Phase Change Based Soft Actuator Enhanced by Antagonistic Effect [J]. | ACS APPLIED ELECTRONIC MATERIALS , 2024 , 7 (1) : 471-479 . |
| MLA | Wei, Fanan et al. "Response Speed of Phase Change Based Soft Actuator Enhanced by Antagonistic Effect" . | ACS APPLIED ELECTRONIC MATERIALS 7 . 1 (2024) : 471-479 . |
| APA | Wei, Fanan , Yang, Lingyun , Lv, Zhen , Yao, Ligang . Response Speed of Phase Change Based Soft Actuator Enhanced by Antagonistic Effect . | ACS APPLIED ELECTRONIC MATERIALS , 2024 , 7 (1) , 471-479 . |
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Abstract ：
Cardiovascular disease is becoming the leading cause of human mortality. In order to address this, flexible continuum robots have emerged as a promising solution for miniaturizing and automating vascular interventional equipment for diagnosing and treating cardiovascular diseases. However, existing continuum robots used for vascular intervention face challenges such as large cross-sectional sizes, inadequate driving force, and lack of navigation control, preventing them from accessing cerebral blood vessels or capillaries for medical procedures. Additionally, the complex manufacturing process and high cost of soft continuum robots hinder their widespread clinical application. In this study, we propose a thermally drawn-based microtubule soft continuum robot that overcomes these limitations. The proposed robot has cross-sectional dimensions several orders of magnitude smaller than the smallest commercially available conduits, and it can be manufactured without any length restrictions. By utilizing a driving strategy based on liquid kinetic energy advancement and external magnetic field for steering, the robot can easily navigate within blood vessels and accurately reach the site of the lesion. This innovation holds the potential to achieve controlled navigation of the robot throughout the entire blood vessel, enabling in situ diagnosis and treatment of cardiovascular diseases.
Keyword ：
cardiovascular cardiovascular magnetic driving magnetic driving microtubule soft continuum robot microtubule soft continuum robot submillimeter submillimeter thermal drawing thermal drawing
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| GB/T 7714 | Wang, Xufeng , Liu, Wei , Luo, Qinzhou et al. Thermally Drawn-Based Microtubule Soft Continuum Robot for Cardiovascular Intervention [J]. | ACS APPLIED MATERIALS & INTERFACES , 2024 , 16 (23) : 29783-29792 . |
| MLA | Wang, Xufeng et al. "Thermally Drawn-Based Microtubule Soft Continuum Robot for Cardiovascular Intervention" . | ACS APPLIED MATERIALS & INTERFACES 16 . 23 (2024) : 29783-29792 . |
| APA | Wang, Xufeng , Liu, Wei , Luo, Qinzhou , Yao, Ligang , Wei, Fanan . Thermally Drawn-Based Microtubule Soft Continuum Robot for Cardiovascular Intervention . | ACS APPLIED MATERIALS & INTERFACES , 2024 , 16 (23) , 29783-29792 . |
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In recent years, designing a soft robot that can jump continuously and quickly explore in a narrow space has been a hot research topic. With the continuous efforts of researchers, many types of actuators have been developed and successfully employed to actuate the rapid locomotion of soft robots. Although these mechanisms have enabled soft robots with excellent movement capabilities, they largely rely on external energy supply cables, which greatly limits their applications. Therefore, it is still a big challenge to realize the unconstrained movement of the soft robot and the flexible adjustment of the movement direction in a narrow space. Here, a wireless magnetically controlled soft jumping robot with single-leg is proposed, which can achieve continuous and rapid jumping motion. What's more interesting is that by changing the frequency and waveform of the control signal, this soft robot can easily switch between forward and backward motions. This motion direction switching function enables the magnetically controlled soft robot to return to the initial position without adjusting the direction when it completes the operation in a narrow pipe or takes the wrong path, which greatly improves the motion efficiency of the soft jumping robot and broadens its application field.
Keyword ：
Bidirectional motion Bidirectional motion Jumping Jumping Magnetically controlled Magnetically controlled Soft robot Soft robot Wireless Wireless
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| GB/T 7714 | Zhong, Tianliang , Wei, Fanan , Zhai, Zhushan et al. An Untethered Miniature Soft Jumping Robot Inspired by Quadrupeds [J]. | JOURNAL OF BIONIC ENGINEERING , 2023 , 20 (4) : 1467-1480 . |
| MLA | Zhong, Tianliang et al. "An Untethered Miniature Soft Jumping Robot Inspired by Quadrupeds" . | JOURNAL OF BIONIC ENGINEERING 20 . 4 (2023) : 1467-1480 . |
| APA | Zhong, Tianliang , Wei, Fanan , Zhai, Zhushan , Yang, Wenguang . An Untethered Miniature Soft Jumping Robot Inspired by Quadrupeds . | JOURNAL OF BIONIC ENGINEERING , 2023 , 20 (4) , 1467-1480 . |
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As an important branch of robotics, soft robots have the advantages of strong flexibility, a simple structure, and high safety. These characteristics enable soft robots to be widely used in various fields such as biomedicine, military reconnaissance, and micro space exploration. However, contemporary soft crawling robots still face problems such as the single drive mode and complex external equipment. In this study, we propose an innovative design of an inchworm-like soft crawling robot utilizing the synergistic interaction of electricity and moisture for its hybrid dual-drive locomotion. The legs of the soft robot are mainly made of GO-CNT/PE composite film, which can convert its own volume expansion into a corresponding bending motion after being stimulated by electricity or moisture. Unlike other drive methods, it requires less power and precision from external devices. The combination of the two driving methods greatly improves the environmental adaptability of the soft robot, and we developed visible light as the driving method on the basis of the dual drive. Finally, we also verified the robot's excellent load capacity, climbing ability, and optical drive effect, which laid the foundation for the application of soft robots in the future.
Keyword ：
biomimetic biomimetic electric-moisture drive electric-moisture drive GO-CNT/PE film GO-CNT/PE film inchworm inchworm soft robot soft robot
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| GB/T 7714 | Wang, Xufeng , Pu, Wei , Zhang, Ruichen et al. Inchworm-like Soft Robot with Multi-Responsive Bilayer Films [J]. | BIOMIMETICS , 2023 , 8 (5) . |
| MLA | Wang, Xufeng et al. "Inchworm-like Soft Robot with Multi-Responsive Bilayer Films" . | BIOMIMETICS 8 . 5 (2023) . |
| APA | Wang, Xufeng , Pu, Wei , Zhang, Ruichen , Wei, Fanan . Inchworm-like Soft Robot with Multi-Responsive Bilayer Films . | BIOMIMETICS , 2023 , 8 (5) . |
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In recent years, there has been significant progress in the development of flexible sensors for human-machine interfaces. However, the triboelectric principle, especially which based on sliding mode, is relative rarely applied to flexible strain sensors. Therefore, a novel triboelectric flexible stretchable sensor has been designed with a simple structure, convenient fabrication process, and effective response to various strain signals (Within the range of 0%-200%, the average sensitivity is 49.07 mV per 1% strain). This sensor operates in a new triboelectric working mode: variable charge density mode (VCD mode). Furthermore, the sensor can also be utilized for tactile sensing in vertical contact-separation mode without any structural modifications. Based on this strain-tactile dual-mode flexible triboelectric sensor (STDFTS), its applications for human-machine interface have been explored: gesture recognition (recognition accuracy of five gestures reaches 99.4%) based on tactile sensing and mouse replacement based on dual working modes. The STDFTS proposed in this article provides a new alternative solution for human-machine interfaces, greatly expanding the application scenarios of triboelectricity. The sensor's innovative design and dual-mode functionality open up new avenues for research and development in the field of triboelectric nanogenerator, flexible sensors and human-machine interaction.
Keyword ：
Human-machine interface Human-machine interface Strain sensor Strain sensor Tactile sensor Tactile sensor Triboelectric nanogenerator Triboelectric nanogenerator Variable charge density Variable charge density
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| GB/T 7714 | Wang, Lin , Wei, Fanan , Zhai, Zhushan et al. A flexible dual-mode triboelectric sensor for strain and tactile sensing toward human-machine interface applications [J]. | SENSORS AND ACTUATORS A-PHYSICAL , 2023 , 365 . |
| MLA | Wang, Lin et al. "A flexible dual-mode triboelectric sensor for strain and tactile sensing toward human-machine interface applications" . | SENSORS AND ACTUATORS A-PHYSICAL 365 (2023) . |
| APA | Wang, Lin , Wei, Fanan , Zhai, Zhushan , Zhang, Ruichen , Liu, Wei , Zhao, Zengxu . A flexible dual-mode triboelectric sensor for strain and tactile sensing toward human-machine interface applications . | SENSORS AND ACTUATORS A-PHYSICAL , 2023 , 365 . |
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Traditional pneumatic soft actuators have been widely used in the field of soft robotics owing to their high output force and large deformation capabilities. However, their bulky pumping systems pose limitations on their portability and miniaturization. In this study, we propose a method of PVA film-assisted manufacturing chamber and design an electrothermal soft actuator based on a phase change material. The actuator makes the phase change material filled in the chamber change into the vapor phase by heating from the embedded electrothermal wire, thus driving the actuator to deform. The actuator designed in this article can achieve a unilateral deformation of 17 mm and an output force of 0.265 N at a voltage of 5 V (the weight of the actuator itself is 1.5 g). In addition, based on the absolute node coordinate method, we adopt the hyperelastic material model, which can well describe the large deformation behavior of this soft structure, to model the actuator.
Keyword ：
absolutenode coordinate method absolutenode coordinate method electrothermal softactuator electrothermal softactuator low voltage drive low voltage drive phase change material phase change material pneumatic actuators pneumatic actuators
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| GB/T 7714 | Wei, Fanan , Zhai, Zhushan , Yang, Lingyun . Low-Voltage-Driven Soft Electrothermal Actuators Based on Phase-Change Materials [J]. | ACS APPLIED ELECTRONIC MATERIALS , 2023 . |
| MLA | Wei, Fanan et al. "Low-Voltage-Driven Soft Electrothermal Actuators Based on Phase-Change Materials" . | ACS APPLIED ELECTRONIC MATERIALS (2023) . |
| APA | Wei, Fanan , Zhai, Zhushan , Yang, Lingyun . Low-Voltage-Driven Soft Electrothermal Actuators Based on Phase-Change Materials . | ACS APPLIED ELECTRONIC MATERIALS , 2023 . |
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Low-dimensional nanomaterials are receiving widespread attention as one ideal material for manufacturing high-performance electronic switches, which play an important role in improving the reliability, working speed and miniaturization of electron devices. This article reviews 16 classes of low-dimensional nanomaterials used to prepare or refine micro-/nanoelectromechanical switches, molecular electrical switches, resistive switches for memory, molecular switches, spin switches and radio frequency switches. By classifying the size difference into zero-dimensional (0D) nanomaterials, one-dimensional (1D) nanomaterials and two-dimensional (2D) nanomaterials, the effect of nanomaterials on the switching performance and the progress of application in related electronic devices are reviewed. By comparison, we discovered the advantages of low-dimensional nanomaterial-based electronic switches compared to conventional semiconductor switches. Finally, the development direction, challenges and opportunities of low-dimensional nanomaterials for improving electronic device performance are presented, and future research directions are predicted.
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| GB/T 7714 | Zhang, Linchen , Xu, Ke , Wei, Fanan . Fabrication of electronic switches based on low-dimensional nanomaterials: a review [J]. | JOURNAL OF MATERIALS SCIENCE , 2023 , 58 (5) : 2087-2110 . |
| MLA | Zhang, Linchen et al. "Fabrication of electronic switches based on low-dimensional nanomaterials: a review" . | JOURNAL OF MATERIALS SCIENCE 58 . 5 (2023) : 2087-2110 . |
| APA | Zhang, Linchen , Xu, Ke , Wei, Fanan . Fabrication of electronic switches based on low-dimensional nanomaterials: a review . | JOURNAL OF MATERIALS SCIENCE , 2023 , 58 (5) , 2087-2110 . |
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