This　study　advances　the　structural　analysis　of　building　performance　under　the　multi-hazard　scenario　of　fire　followed　by　an　explosion.　Using　validated　numerical　simulations,　the　dynamic　response　of　steel-reinforced　concrete-filled　steel　tubular　(SRCFST)　columns　is　assessed.　A　parametric　analysis　investigated　the　influence　of　fire　duration,　axial　compression　ratio,　scaled　distance,　and　explosion　angle　to　enhance　system　safety　and　reliability.　Results　show　prolonged　fire　severely　degrades　column　stiffness.　An　axial　compression　ratio　below　0.2　is　beneficial,　but　ratios　of　0.5　or　higher　lead　to　failure.　Scaled　distances　of　0.22　m/kg1/3　or　less　cause　critical　damage.　Larger　explosion　angles　(approaching　45°)　improve　blast　resistance.　These　findings　provide　critical　data　for　the　design　of　safer,　more　resilient　structures　in　the　built　environment,　contributing　to　building　sustainability　and　safety.　©　2025　The　Authors