There　are　a　number　of　iron　deposits　with　skarn　mineral　assemblages　in　the　Makeng-Yangshan　region,　southeast　China.　In　this　paper,　we　describe　the　geology　of　the　Yangshan　iron　deposit　and　present　new　mineral　and　fluid　inclusion　data　for　this　deposit　to　provide　new　insights　into　its　genesis　and　fluid　evolution.　Iron　orebodies　were　mainly　located　at　the　contact　zone　between　the　ca.130　Ma　Yangshan　granite　and　Carboniferous-Permian　carbonate　strata.　The　iron　ores　mainly　consist　of　magnetite,　garnet,　pyroxene,　amphibole,　and　quartz.　Magnetites　in　the　prograde　skarn　stage　show　Mn　(0.12–2.17　wt%)　and　Mg　contents　(0.01–2.17　wt%),　whereas　those　from　the　retrograde　skarn　and　quartz-sulfide　stages　exhibit　high　Al　(0.10–1.38　wt%)　and　high　Ca　contents　(0.13–0.99　wt%),　respectively.　Fluid　inclusion　studies　show　that　the　prograde　skarn　stage　formed　by　relatively　high-temperature　(450–550　°C)　and　low-　to　high-salinity　(3.3–11.7　wt%　NaCl　eqv　and　＞　29.6　wt%　NaCl　eqv)　fluids.　The　coexistence　of　vapor-　and　liquid-rich　inclusions　suggests　fluid　boiling　occurred　at　this　stage,　which　led　to　the　precipitation　of　main　magnetite　ores.　The　temperatures　and　salinities　of　retrograde　skarn　stage　(260–400　°C　and　6.6–13.0　wt%　NaCl　eqv)　and　quartz-sulfide　stage　(140–300　°C　and　0.8–16.8　wt%　NaCl　eqv)　generally　decreased.　Moreover,　a　comprehensive　analysis　of　ore-forming　processes　was　conducted　among　the　Makeng,　Luoyang,　and　Yangshan　iron　deposits　in　southeast　China,　yielding　an　integrated　metallogenic　model　linking　iron　mineralization　with　evolving　skarn　system.　The　newly　established　genetic　model　can　provide　new　insights　into　the　ore-forming　mechanisms　of　iron　skarn　metallogenic　belt　in　southeast　China.　©　2025　Elsevier　Ltd