Organic　nonlinear　optical　(NLO)　materials　with　strong　light-responsive　properties　have　garnered　significant　attention　in　the　field　of　optoelectronics　due　to　their　chemical　tunability　and　cost-effective　synthesis.　Enhancing　the　NLO　performance　of　these　materials　is　essential　to　meet　the　growing　demands　in　applications　such　as　optical　modulation　and　communication.　Interestingly,　twisted　structures　have　been　shown　to　alter　NLO　properties,　offering　a　novel　design　approach.　This　review　systematically　examines　recent　advances　in　twisted　D-pi-A　type　organic　chromophores　for　enhancing　NLO　performance,　with　a　particular　focus　on　the　key　mechanisms　of　molecular　structure　design　and　performance　optimization.　It　provides　a　detailed　discussion　of　the　design　strategies　aimed　at　improving　the　NLO　performance　of　twisted　organic　chromophores,　highlighting　the　significance　of　twisted　structures　and　electronic　group　design.　The　literature　review　indicates　that　optimizing　twist　angles,　strengthening　donor　and　acceptor　group　intensities,　and　optimizing　pi-conjugated　bridges　are　effective　ways　to　enhance　NLO　performance.