During　the　synthesis　of　dyes,　desalination　of　high-salinity　dye-containing　waste　liquor　is　a　critical　premise　for　high-quality,　clean　dye　production.　Conventional　membrane　processes,　such　as　electrodialysis,　nanofiltration　and　ultrafiltration,　are　inevitably　subjected　to　serious　membrane　fouling,　deteriorating　the　dye/salt　fractionation　efficacy.　Integrating　the　technical　merits　of　electrodialysis　and　pressure-driven　membrane　separation,　we　devise　an　electro-driven　filtration　process　using　a　tight　ultrafiltration　membrane　as　alternative　to　conventional　anion　exchange　membrane　for　rapid　anion　transfer,　in　view　of　dye　desalination　and　purification.　By　employing　a　sub-4　nanometer　tight　ultrafiltration　membrane　as　anion　conducting　membrane,　the　electro-driven　filtration　process　achieves　98.15%　desalination　efficiency　and　99.66%　dye　recovery　for　one-step　fractionation　of　reactive　dye　and　NaCl　salt,　markedly　outperforming　the　system　using　commercial　anion　exchange　membranes.　Notably,　the　electro-driven　filtration　system　displays　a　consistently　high　and　stable　fractionation　performance　for　dyes　and　salts　with　unprecedentedly　low　membrane　fouling　through　an　eight-cycle　continuous　operation.　Our　results　demonstrate　that　the　electro-driven　filtration　process　using　nanoporous　membranes　as　high-performance　anion　conducting　membranes　shows　a　critical　potential　in　fractionation　of　organic　dyes　and　inorganic　salts,　unlocking　the　proof　of　concept　of　nanoporous　membranes　in　electro-driven　application.