Background　Magnesium　regulates　vascular　smooth　muscle　contraction,　with　implications　for　cardiovascular　diseases.　However,　the　population-level　relevance　of　magnesium　homeostasis　to　urinary　incontinence　(UI)　subtypes　and　associated　mortality　remains　unexamined.Methods　The　National　Health　and　Nutrition　Examination　Survey　(NHANES)　were　utilized　to　investigate　the　association　between　magnesium　depletion　score　(MDS)　and　urinary　incontinence　(UI)　from　2005　to　2018.　Weighted　multivariate　regression　analyses　and　multivariate　Cox　regression　analyses　were　used　to　analysis.　Additionally,　subgroup　analyses　and　multiple　imputations　(MI)　were　carried　out　as　sensitivity　analyses　to　ensure　the　strength　and　reliability　of　the　findings.Results　A　total　of　16,197　individuals　were　included　in　the　study,　with　6,881　of　them　experiencing　urinary　incontinence　(UI).　Among　those　with　UI,　767　cases　of　all-cause　mortality　were　documented.　The　prevalence　rates　were　42.83%　for　stress　urinary　incontinence　(SUI),　27.85%　for　urgency　urinary　incontinence　(UUI),　and　16.82%　for　mixed　urinary　incontinence　(MUI).　Results　from　weighted　logistic　regression　analysis　demonstrated　a　positive　relationship　between　MDS　and　SUI　(OR　1.09,　95%　CI:　1.01-1.17),　UUI　(OR　1.14,　95%　CI:　1.06-1.22),　and　MUI　(OR　1.22,　95%　CI:　1.11-1.35).　Additionally,　higher　MDS　values　were　associated　with　increased　severity　of　urinary　incontinence.　These　findings　were　further　supported　by　various　sensitivity　analyses.　Furthermore,　survey-weighted　Cox　proportional　hazards　regression　indicated　a　positive　association　between　MDS　and　all-cause　mortality　regardless　of　(OR　1.27,　95%　CI:　1.13-1.41),　suggesting　that　higher　MDS　independently　predicts　worse　prognosis.Conclusion　MDS　is　an　important　risk　factor　for　the　prevalence　and　mortality　rates　of　UI.　Monitoring　magnesium　status　may　inform　UI　prevention　strategies.　Interpretation　should　consider　limitations　including　observational　design　and　lack　of　serum　magnesium　levels.