Liquid　crystals，with　their　multifunctional　and　tunable　properties，have　garnered　significant　attention　in　the　field　of　information　security.　Due　to　their　unique　molecular　structures　and　phase　transition　properties，liquid　crystals　can　alter　their　characteristics　in　response　to　external　stimuli，such　as　reversible　switching　between　light　scattering　and　transparent　states，　dynamic　changes　in　structural　color，　and　variations　in　rigidity.　Through　doping　stimuli-responsive　molecules　or　dyes　into　the　liquid　crystal　matrix，　it　can　not　only　improve　the　physical　and　optical　properties　of　the　liquid　crystals，but　also　impart　additional　stimulus-responsive　functions，or　even　multiple　stimuli　responses，thus　enabling　multi-mode　or　multi-level　dynamic　information　storage.　Applying　liquid　crystal　materials　to　anti-counterfeiting　labels　enables　efficient　and　visual　authentication　of　products　and　documents，effectively　countering　forgery　and　tampering.　This　article　reviews　the　latest　technological　advancements　of　liquid　crystal　materials　in　the　fields　of　encryption　and　anti-counterfeiting.　It　systematically　introduces　the　design　and　manufacturing　strategies　of　stimulus-responsive　liquid　crystal　materials，and　their　response　mechanisms　under　single　and　multiple　stimuli，　such　as　light，　heat，　stress，　humidity　and　electricity，　and　discusses　specific　application　cases　in　encryption　and　anti-counterfeiting.　Finally，the　prospect　and　challenges　of　liquid　crystal　materials　in　the　field　of　information　security　are　introduced.　This　review　provides　important　guidance　for　the　design　and　development　of　in　liquid　crystal　materials　in　encryption　and　anti-counterfeiting　applications.　©　2025,　Science　Press.　All　rights　reserved.