The　widespread　use　of　plastics　has　led　to　significant　environmental　pollution,　but　microplastics　(MPs)　have　had　a　noteworthy　impact　in　this　regard　and　serve　as　carriers　for　various　toxic　pharmaceuticals.　Therefore,　there　is　a　need　to　design　a　water　treatment　process　capable　of　simultaneously　removing　MPs　and　pharmaceuticals.　In　this　study,　a　novel　photocatalytic　membrane,　composed　of　a　binary　C3N4/Bi12O17Cl2　(CN/BOC)　heterojunction　immobilized　on　a　polyacrylonitrile　(PAN)　membrane　via　electrospinning,　is　developed　to　address　this　issue.　Comprehensive　characterizations　confirm　the　formation　of　a　heterojunction　structure　that　optimizes　charge　separation　and　prolongs　electron　lifetime.　The　CN/BOC/PAN　photocatalytic　membrane　demonstrates　100　%　removal　efficiency　for　19　out　of　20　types　of　mixed　pharmaceuticals　within　180　min.　Additionally,　the　membrane　converts　polylactic　acid　(PLA)　into　value-added　organic　acids,　thereby　offering　a　sustainable　approach　to　plastic　upcycling.　The　highest　occupied　molecular　orbital　(HOMO),　lowest　unoccupied　molecular　orbital　(LUMO),　and　Fukui　index　are　employed　to　identify　the　active　sites　for　carbamazepine　(CBZ)　and　PLA　degradation.　This　study　provides　new　insights　into　the　photocatalytic　removal　of　pharmaceuticals　and　MPs,　highlighting　the　potential　for　remediating　water-borne　contaminants.　©　2025