It　remains　challenges　for　conversion　of　CO2-derived　alcohol　into　electrical　energy　while　without　CO2　greenhouse　gases　emission.　Herein,　a　novel　sustainable　CO2-emssion　free　direct　alcohol　fuel　cell　(DAFC)　is　developed　by　using　Pt-Au/nickel　mesh　anode　with　highly　selective　electrocatalytic　oxidation　of　alcohol　to　acetate　value-added　chemicals.　The　DAFC　demonstrate　a　peak　power　density　of　72.9　mW　cm-2　and　simultaneously　co-synthesis　25　mol　of　acetate　per　1　kWh　of　electrical　energy　output.　This　study　realizes　the　clean　and　efficient　use　of　CO2-derived　carbon-based　fuels,　highly　selective　synthesis　of　acetate　under　mild　conditions　and　generating　electricity　while　without　CO2　greenhouse　gases　emission,　realizing　a　＂negative　carbon＂　cycle　for　sustainable　development.