Para-arsanilic　acid　(p-ASA)　is　widely　used　as　a　feed　additive,　making　it　a　pervasive　environmental　pollutant.　Due　to　its　migratory　and　transformative　nature,　p-ASA　can　easily　convert　into　more　toxic　inorganic　arsenic　during　its　migration,　thereby　increasing　the　ecological　burden　and　posing　a　threat　to　human　health.　Efficient　removal　of　p-ASA　from　water　is　crucial　for　mitigating　arsenic　contamination.　Efficient　removal　of　p-ASA　from　water　is　crucial　for　mitigating　arsenic　contamination.　This　study　introduced　zirconium-loaded　collagen　fiber　membrane　(CFM[sbnd]Zr),　a　novel,　sustainable　membrane　adsorption　material　synthesized　by　retanning　collagen　fiber　membranes　(CFM)　with　zirconium　(Zr).　Leveraging　the　physicochemical　properties　of　CFM　and　the　strong　affinity　of　Zr　for　p-ASA,　CFM-Zr　achieved　highly　efficient　p-ASA　removal.　The　resulting　membrane　was　made　entirely　from　green,　low-carbon　and　recyclable　raw　materials,　achieving　sustainable　removal　of　p-ASA　while　realizing　the　concept　of　treating　waste　with　waste　for　environmental　recovery.　Remarkably,　the　retanning　with　zirconium　significantly　enhanced　the　Zeta　potential　of　CFM[sbnd]Zr,　strengthening　its　electrostatic　attraction　to　p-ASA,　with　a　maximum　adsorption　capacity　of　289.02　mg·g−1,　which　was　19.72　times　higher　than　that　of　the　CFM　before　retanning　(13.95　mg·g−1).　Its　adsorption　rate　constant　was　12.54　mg·g−1·min−1.　Moreover,　CFM-Zr　showed　good　reusability　and　exhibited　electrostatic　adsorption　and　metal　coordination　effects　on　the　“organic”　parts　(-OH,　-NH2)　and　“inorganic”　parts　(As[sbnd]O)　of　p-ASA,　effectively　removing　it.　This　work　provided　a　promising　bio-based　material　for　water　purification,　promoted　the　sustainable　utilization　of　leather　industry　waste,　and　offered　significant　advancements　in　environmental　remediation　and　resource　recovery.　©　2025