Conducting　polymers(CPs),including　poly(3,4-ethylenedioxythiophene):poly(styrenesulfonate)(PEDOT:PSS),are　promis-ing　coating　materials　for　neural　electrodes.However,the　weak　adhesion　of　CP　coatings　to　substrates　such　as　platinum-iridium　is　a　significant　challenge　that　limits　their　practical　application.To　address　this　issue,we　used　femtosecond　laser-prepared　hierarchical　structures　on　platinum-iridium(Pt-Ir)substrates　to　enhance　the　adhesion　of　PEDOT:PSS　coatings.Next,we　used　cyclic　voltammetry(CV)stress　and　accelerated　aging　tests　to　evaluate　the　stability　of　both　drop　cast　and　electrodeposited　PEDOT:PSS　coatings　on　Pt-Ir　substrates,both　with　and　without　hierarchical　structures.Our　results　showed　that　after　2000　CV　cycles　or　five　weeks　of　aging　at　60℃,the　morphology　and　electrochemical　properties　of　the　coatings　on　the　Pt-Ir　substrates　with　hierarchical　structures　remained　relatively　stable.In　contrast,we　found　that　smooth　Pt-Ir　substrate　surfaces　caused　delamination　of　the　PEDOT:PSS　coating　and　exhibited　both　decreased　charge　storage　capacity　and　increased　impedance.Overall,enhancing　the　stability　of　PEDOT:PSS　coatings　used　on　common　platinum-iridium　neural　electrodes　offers　great　potential　for　improving　their　electrochemical　performance　and　developing　new　functionalities.