A　visible　light-promoted　fast　photochemical　Wolff　rearrangement　was　developed　toward　synthesis　of　alpha-substituted　amides　in　continuous　flow　with　the　use　of　a　photochemical　oscillatory　flow　reactor　(POFR).　The　control　experiment　indicates　that　a　fast　process　of　the　Wolff　rearrangement　(＜40　s)　is　involved.　Notably,　this　protocol　does　not　require　excess　use　of　any　reactants,　and　the　resulting　alpha-substituted　amides　could　be　isolated　by　recrystallization　in　good　to　excellent　yields.　(c)　2024　Published　by　Elsevier　B.V.　on　behalf　of　Chinese　Chemical　Society　and　Institute　of　Materia　Medica,　Chinese　Academy　of　Medical　Sciences.