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author：

Tian, H. (Tian, H..) [1] | Hu, Y. (Hu, Y..) [2] | Wu, J. (Wu, J..) [3] | Wang, R. (Wang, R..) [4] | Wang, J. (Wang, J..) [5] | Cai, X. (Cai, X..) [6] | Chen, X. (Chen, X..) [7] | He, Y. (He, Y..) [8] | Wang, S. (Wang, S..) [9]

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EI Scopus SCIE

Abstract：

3D　printing　of　bio-hydrogel　scaffolds　are　widely　used　in　tissue　regeneration.　However,　due　to　the　ultra-soft　properties　of　bio-hydrogels,　it　is　hard　to　print　them　precisely.　Here,　crystal　transduction　3D　printing　with　high　fidelity　is　proposed　to　address　this　challenge.　A　phase-transition　bio-inks　system　with　beeswax　is　developed　for　crystal　transduction,　which　can　accelerate　energy　consumption　and　induce　soft　bio-inks　to　quickly　harden　during　printing.　Interestingly,　an　interconnected　porous　hydrogel　scaffold　can　be　obtained　after　washing　the　crystal　beeswax.　The　porous　hydrogel　scaffold　demonstrated　excellent　biocompatibility　and　cell　proliferation　effect　in　vitro　and　is　free　from　defense　responses　and　immunogenicity　in　vivo.　Muscle　analog　porous　scaffolds　constructed　by　high-fidelity　3D　printing　significantly　improve　the　tissue　function　recovery　of　rats　with　muscle　defects,　compared　with　the　conventional　printed　hydrogel　with　a　non-matched　shape.　These　structure-performance　design　rules　create　exciting　opportunities　to　customize　3D-printed　porous　hydrogel　scaffolds　with　high　fidelity.　©　2024　Wiley-VCH　GmbH.

Keyword：

3D printing crystal transformations energy consumptions high fidelity porous hydrogel scaffolds

Community：

  • [ 1 ] [Tian H.]College of Chemical Engineering, College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 2 ] [Hu Y.]College of Chemical Engineering, College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 3 ] [Wu J.]College of Chemical Engineering, College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 4 ] [Wang R.]College of Chemical Engineering, College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 5 ] [Wang J.]The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang, Hangzhou, 310009, China
  • [ 6 ] [Cai X.]College of Chemical Engineering, College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 7 ] [Cai X.]Qingyuan Innovation Laboratory, Fujian, Quanzhou, 362801, China
  • [ 8 ] [Cai X.]Marine Green Processing Research Center, Fuzhou Institute of Oceanography, Fujian, Fuzhou, 350108, China
  • [ 9 ] [Chen X.]College of Chemical Engineering, College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 10 ] [Chen X.]Qingyuan Innovation Laboratory, Fujian, Quanzhou, 362801, China
  • [ 11 ] [Chen X.]Marine Green Processing Research Center, Fuzhou Institute of Oceanography, Fujian, Fuzhou, 350108, China
  • [ 12 ] [He Y.]The Second Affiliated Hospital of Zhejiang University, School of Medicine, Zhejiang, Hangzhou, 310009, China
  • [ 13 ] [Wang S.]College of Chemical Engineering, College of Biological Science and Engineering, Fuzhou University, Fujian, Fuzhou, 350108, China
  • [ 14 ] [Wang S.]Qingyuan Innovation Laboratory, Fujian, Quanzhou, 362801, China
  • [ 15 ] [Wang S.]Marine Green Processing Research Center, Fuzhou Institute of Oceanography, Fujian, Fuzhou, 350108, China

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Source ：

Advanced Functional Materials

ISSN： 1616-301X

Year： 2024

Issue： 8

Volume： 35

1 8 . 5 0 0

JCR@2023

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ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 2

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