Lead　halide　perovskites　have　garnered　attention　as　promising　electrochemiluminescence　(ECL)　emitters　owing　to　their　superior　photophysical　characteristics.　However,　their　poor　water　stability　severely　restricts　their　application　in　aqueous　media　for　ECL.　In　this　study,　inorganic　perovskite　CsPbBr3　was　assembled　in　situ　in　the　imine-linked　covalent-organic　framework　(COF-LZU1)　as　a　novel　ECL　emitter.　The　expansive　surface　area　and　robust　hydrophobic　architecture　of　COF-LZU1　not　only　improved　the　water　stability　of　CsPbBr3　but　also　guaranteed　its　exceptional　ECL　performance.　The　novel　composite　nanoluminescent　material　was　coated　onto　an　indium　tin　oxide　(ITO)　electrode　via　spin-coating　and　calcination　processes　to　serve　as　an　electrochemiluminescence　(ECL)　platform.　A　sensor　was　developed　by　combining　a　DNA　hydrogel　target-induced　release　system　with　a　platform　using　ascorbic　acid　(AA)　as　a　coreactant　and　T-2　toxin　as　the　target　analyte　model.　This　method　achieved　a　detection　limit　as　low　as　3.56　fg·mL-1　and　was　successfully　applied　to　the　analysis　of　the　T-2　toxin　content　in　corn　samples.　This　study　offers　a　novel　path　for　the　advancement　of　perovskite-based　ECL　emitters　and　their　utilization　in　aqueous　environments　within　the　ECL　field.　©　2024　American　Chemical　Society.