Conductive　organohydrogels　are　promising　for　strain　sensing,　while　their　weak　mechanical　properties,　poor　crack　propagation　resistance　and　unstable　sensing　signals　during　long-term　use　have　seriously　limited　their　applications　as　high-performance　strain　sensors.　Here,　we　propose　a　facile　method,　i.e.,　solvent　exchange　assisted　hot-pressing,　to　prepare　strong　yet　tough,　transparent　and　anti-fatigue　ionically　conductive　organohydrogels　(ICOHs).　The　densified　polymeric　network　and　improved　crystallinity　endow　ICOHs　with　excellent　mechanical　properties.　The　tensile　strength,　toughness,　fracture　energy　and　fatigue　threshold　of　ICOHs　can　reach　36.12　+/-　4.15　MPa,　54.57　+/-　2.89　MJ　m-3,　43.44　+/-　8.54　kJ　m-2　and　1212.86　+/-　57.20　J　m-2,　respectively,　with　a　satisfactory　fracture　strain　of　266　+/-　33%.　In　addition,　ICOH　strain　sensors　with　freezing　and　drying　resistance　exhibit　excellent　cycling　stability　(10　000　cycles).　More　importantly,　the　fatigue　resistance　allows　the　notched　strain　sensor　to　work　normally　with　no　crack　propagation　and　output　stable　and　reliable　sensing　signals.　Overall,　the　unique　flaw-insensitive　strain　sensing　makes　ICOHs　promising　in　the　field　of　wearable　and　durable　electronics.　Strong,　transparent　and　anti-fatigue　ionically　conductive　organohydrogels　are　prepared　using　a　solvent　exchange　assisted　hot-pressing　method.　The　tensile　strength　and　fatigue　threshold　of　ICOHs　can　reach　36.12　MPa　and　1212.86　J　m-2,　respectively.