Currently,　antibiotics　are　extensively　utilized　in　the　pharmaceutical　industry　to　assist　humans　and　animals　in　combating　various　infectious　diseases.　The　extensive　use　of　various　antibiotics　enhances　the　quality　of　life.　However,　it　can　also　have　negative　effects　on　the　environment　and　human　health,　including　water　pollution　and　the　rise　of　antibiotic-resistant　microorganisms.　To　date,　antibiotics　have　been　detected　in　rivers,　groundwater,　and　even　drinking　water.　There　is　an　urgent　need　to　design　and　develop　advanced　materials　for　the　remediation　of　antibiotics　present　in　our　environment.　In　this　paper,　we　successfully　synthesized　a　novel　Ag2S-ZnS/ZIF-8　hollow　heterojunction　via　facile　sulphuration　and　solvothermal　methods.　This　heterojunction　was　employed　as　a　catalyst　for　the　degradation　of　tetracycline　(TC)　in　water　under　UV　and　visible　light　irradiation.　The　physicochemical　properties　of　the　as-synthesized　catalysts　were　thoroughly　analyzed　using　XRD,　EDS,　SEM,　BET,　XPS,　TEM,　ESR,　UV-vis　techniques.　The　results　demonstrate　that　Ag2S-ZnS/ZIF-8　displays　enhanced　photocatalytic　activity　for　TC　degradation　no　matter　under　visible　or　UV　light　irradiation.　After　10　min　of　UV　light　irradiation,　its　photocatalytic　degradation　efficiency　was　achieved　92.74　%.　Additionally,　Ag2S-ZnS/ZIF-8　was　able　to　degrade　92.14　%　of　TC　(visible　light,　with　35　min).　The　corresponding　kinetic　rate　constant　of　Ag2S-ZnS/ZIF-8　is　0.145　min(-1)　(UV　light)　and　0.043　min(-1)　(visible　light),　respectively.　Furthermore,　Ag2S-ZnS/ZIF-8　also　shown　excellent　stability　for　the　degradation　of　TC　in　the　presence　of　visible　light.　This　is　a　result　of　its　high　specific　surface　area,　superior　photocurrent　and　efficient　separation　of　photo-generated　electrons-hole　pairs.　Apart　from　this,　the　photocatalytic　degradation　mechanism　of　TC　over　Ag2S-ZnS/ZIF-8　is　discussed　in　detail.