Slow　rebound　polyurethane　foam　(SPUF)　has　been　widely　used　due　to　its　advantages　such　as　sound　insulation,　energy　absorption,　and　good　tactile　sensation.　However,　SPUF　is　prone　to　harden　at　low　temperature,　and　its　application　in　medical　equipment　and　households　requires　significant　antibacterial　properties.　In　this　paper,　self-made　silicone　modified　polyethylene　glycol　(Si-APEG)　and　graphene　oxide　supported　allicin　(Alc@GO)　were　prepared　and　used　as　low-temperature　resistant　agent　and　antibacterial　agent,　respectively.　Low-temperature　resistant　polyurethane　foam　(LSPUF)　and　antibacterial　LSPUF　(ALSPUF)　were　prepared　respectively　with　water　as　foaming　agent.　The　morphology　of　ALSPUF　was　observed　by　scanning　electron　microscope.　Properties　studied　include　apparent　core　density　and　porosity,　mechanical　properties　including　tensile　strength,　40%　compressive　hardness,　and　rebound　resilience,　as　well　as　low-temperature　resistance.　Effects　of　Si-APEG　content　on　the　structures　and　properties　were　analyzed　and　the　LSPUF　with　an　Si-APEG　content　of　10　wt.%　showed　the　best　comprehensive　performance.　Therefore,　ALSPUFs　with　Si-APEG　content　of　10　wt.%　and　Alc@GO　content　of　0–3　wt.%　were　prepared.　The　addition　of　Alc@GO　increased　the　antibacterial　ratio　significantly　without　obvious　effect　on　the　structure　and　mechanical　properties　of　LSPUF.　The　antibacterial　ratio　of　ALSPUF　reached　99.07%　at　a　Alc@GO　content　of　2.5　wt.%　and　testing　time　of　60　min.　This　work　provides　an　effective　and　feasible　method　for　the　preparation　of　ALSPUF　which　can　be　widely　used　in　medical　devices　and　households.　Highlights:　Silicone　modified　polyether　is　a　suitable　low-temperature　resistant　agent　for　PU　foam.　Allicin　supported　on　GO　provides　good　antibacterial　property　for　PU　foam.　ALSPUF　has　better　mechanical　properties　than　SPU.　©　2024　Society　of　Plastics　Engineers.