Enhancing　catalyst　durability　is　a　critical　concern　in　the　partial　oxidation　of　methane　(POM)　to　syngas　since　the　reaction　is　operated　at　high　temperatures　(＞600　°C).　Alongside　sintering　and　coke　deposition,　the　deactivation　of　the　supported　Ni　catalyst　is　often　due　to　the　in　situ　oxidation　of　active　metallic　nanoparticles　into　inactive　cations　during　the　POM　reaction.　Herein,　a　Ni/BN　catalyst　was　developed　by　introducing　functional　CeOx　as　a　promoter　to　stabilize　the　Ni　sites.　The　optimized　4Ni/7.5Ce/BN　catalyst,　comprising　4　wt　%　Ni　and　7.5　wt　%　Ce　on　BN,　exhibits　enhanced　stability　during　continuous　testing　at　600　°C　for　125　h　without　any　deactivation,　which　is　comparable　to　that　of　noble　metal　catalysts.　Comprehensive　investigations　reveal　that　maintaining　the　metallic　state　of　Ni　under　reaction　atmosphere　is　crucial　for　the　stability　of　the　catalyst.　The　construction　of　CeOx　on　BN　effectively　inhibits　migration　and　oxidation　of　the　catalytically　active　Ni0　species.　©　2024　American　Chemical　Society.