Metal-halide　perovskite　solar　cells　(PSCs),　an　emerging　technology　for　transforming　solar　energy　into　a　clean　source　of　electricity,　have　reached　efficiency　levels　comparable　to　those　of　commercial　silicon　cells.　Compared　with　other　types　of　PSCs,　inverted　perovskite　solar　cells　(IPSCs)　have　shown　promise　with　regard　to　commercialization　due　to　their　facile　fabrication　and　excellent　optoelectronic　properties.　The　interlayer　interfaces　play　an　important　role　in　the　performance　of　perovskite　cells,　not　only　affecting　charge　transfer　and　transport,　but　also　acting　as　a　barrier　against　oxygen　and　moisture　permeation.　Herein,　we　describe　and　summarize　the　last　three　years　of　studies　that　summarize　the　advantages　of　interface　engineering-based　advances　for　the　commercialization　of　IPSCs.　This　review　includes　a　brief　introduction　of　the　structure　and　working　principle　of　IPSCs,　and　analyzes　how　interfaces　affect　the　performance　of　IPSC　devices　from　the　perspective　of　photovoltaic　performance　and　device　lifetime.　In　addition,　a　comprehensive　summary　of　various　interface　engineering　approaches　to　solving　these　problems　and　challenges　in　IPSCs,　including　the　use　of　interlayers,　interface　modification,　defect　passivation,　and　others,　is　summarized.　Moreover,　based　upon　current　developments　and　breakthroughs,　fundamental　and　engineering　perspectives　on　future　commercialization　pathways　are　provided　for　the　innovation　and　design　of　next-generation　IPSCs.　©　2024　American　Chemical　Society.