To　mitigate　the　profound　impact　of　Microcystis　aeruginosa　algal　bloom　outbreaks　on　aquatic　ecosystems　and　human　health,　a　piezoelectric　T-BaTiO3/Ag3PO4-PVDF　composite　photocatalyst　(T-BTO/AP-PVDF)　was　successfully　synthesized　in　this　study.　The　catalyst　inactivated　97.12%　of　Microcystis　aeruginosa　within　4　h　by　the　combined　effect　of　ultrasound　and　sunlight,　and　the　inactivation　rate　remained　above　88%　after　five　cycles　of　reuse,　which　exhibits　excellent　inactivation　effectiveness　and　stability.　Under　the　conditions　of　piezo-photocatalytic,　the　analysis　of　the　physiological　properties　of　algal　cells　showed　that　T-BTO/AP-PVDF　produced　a　large　amount　of　•OH,　which　were　active　species　that　could　effectively　inactivate　the　algal　cells　and　promote　the　degradation　of　organic　matter,　thus　preventing　the　occurrence　of　secondary　pollution.　The　composite　photocatalysts　were　characterized　using　XRD,　SEM,　XPS,　FTIR,　PFM,　and　WCA.　Combined　with　the　results　of　quenching　experiments,　possible　mechanisms　for　the　inactivation　of　Microcystis　aeruginosa　by　T-BTO/AP-PVDF　were　proposed.　The　application　results　in　actual　water　bodies　further　proved　that　T-BTO/AP-PVDF　is　a　new　method　for　effectively　inhibiting　cyanobacterial　bloom　outbreaks　and　shows　promising　potential　for　application.　©　2024　Elsevier　B.V.