The　intricate　spatial　fiber　winding　structure　of　SiCf/SiC　ceramic　matrix　composite　(CMC)　cladding　tubes　makes　it　difficult　to　investigate　in　depth　the　inherent　evolutionary　mechanism　of　damage　failure　under　specific　operating　conditions.　Therefore,　in　this　study,　based　on　X-ray　computed　tomography　(X-CT)　reconstruction　and　cross　scale　numerical　simulation　methods,　combined　with　clamping　failure　experiments　under　specific　conditions　for　the　cladding　tubes,　we　conduct　an　in-depth　analysis　of　the　material＇s　damage,　failure,　and　mechanical　behavior　in　different　clamped　regions.　The　research　indicates　that　variations　in　the　clamped　regions　have　a　minimal　impact　on　the　overall　mechanical　feedback　of　the　material,　and　the　maximum　clamping　load　remains　essentially　around　500　N.　The　tube　damage　exhibits　a　unique　“　regional　progressive　damage　evolution　mechanism,”　where　stress　differentials　of　108.49–115.33%　appear　between　the　inner　and　outer　surfaces　in　different　regions,　leading　to　variations　in　the　initiation　and　propagation　of　cracks　within　these　areas.　Furthermore,　based　on　the　minimum　potential　energy　principle　and　semi-geodesic　line　theory,　the　intricate　macroscopic　tube　structure　formed　by　the　spatial　stacking　and　winding　of　SiCf/SiC　cladding　tube　fibers　is　accurately　reconstructed,　which　is　combined　with　macroscale　and　microscale　local　feature　models　to　capture　the　fibre/matrix　morphology　of　the　material　with　dynamic　mechanical　feedbacks,　and　experimentally　validated　in　this　work.　The　results　indicate　that　the　numerical　model　can　effectively　characterize　the　complex　mechanical　damage　morphology　and　progressive　failure　lows　of　SiCf/SiC　CMC　at　multiscale.　Simultaneously,　it　is　observed　that　stress　concentrations　in　the　fiber　crossover　region　result　in　a　load-bearing　capacity　112–283%　higher　than　in　other　areas.　This　phenomenon　often　leads　to　the　first　occurrence　of　failure　in　this　region　after　clamping　overload,　exhibiting　more　pronounced　damage　characteristics.　©　2024　Elsevier　Ltd