From　a　human-centric　perspective,　improving　the　spatial　quality　of　historical　districts　is　a　key　focus　in　achieving　their　refined　governance.　Based　on　a　public　survey　performed　in　Zhangzhou　Ancient　City,　we　explored　the　differences　in　the　perception　of　cultural　landscape　genes　(CLGs)　between　residents　and　tourists　with　different　individual　characteristics,　utilizing　non-parametric　tests　and　box-plot　analysis　methods.　The　findings　indicate　the　following:　Tourists　have　a　stronger　perception　of　CLGs　related　to　site　layout　and　architectural　features　than　residents,　while　residents　have　a　stronger　perception　of　cultural　customs.　Gender-related　differences　in　the　perception　of　CLG　are　only　significant　among　tourists,　with　females　showing　a　higher　level　of　CLG　perception　than　males.　Residents　of　different　age　groups　show　a　“U-shaped”　distribution　in　their　perception　of　CLGs　related　to　site　layout,　whereas　senior　tourists　have　a　lower　cognitive　perception　level.　People　with　lower　educational　backgrounds　among　residents　tend　to　perceive　cultural　customs　more　significantly,　whereas　tourists　with　diverse　educational　backgrounds　do　not　perceive　them　as　having　a　significant　impact.　Residence　location,　visit　frequency,　duration　of　residence,　and　residence　nature　are　key　positive　factors　affecting　the　perception　of　CLGs.　Our　study　highlights　the　significance　of　considering　the　users’　characteristics　in　enhancing　the　refined　governance　of　historical　districts.　©　2024　by　the　authors.