This　study　combines　the　accumulation　effects　of　rich　microporous　ZIF-8　metal-organic　framework（MOF）and　the　electrochemical　technology　for　the　metal　ions，and　the　controllable　ability　of　microfluidic　devices　for　the　flowing　of　solution，to　construct　a　new　type　of　sensor　to　achieve　high-throughput，real-time　and　rapid　detection　of　multiple　metal　ion　contaminations　in　the　environment.　The　developed　ZIF-8-Nafion/ITO-based　microfluidic　electro⁃　chemical　sensors　have　a　good　linear　relationship　for　Cd2+，Pb2+　and　Hg2+　ions　in　the　concentration　range　of　0.1—100　μmol/L　with　the　detection　limit　of　0.055，0.0025　and　0.0016　μmol/L，respectively（S/N=3）.　The　microfluidic　chips　require　less　sample　volume　which　reduces　energy　consumption；at　the　same　time，the　microfluidic　devices　made　up　of　polydimethylsiloxane　are　also　expected　to　realize　the　function　of　flexible　electrodes，which　is　important　for　the　integrated　and　automatic　detection　of　biological　and　environmental　samples　using　portable　and　flexible　electrochemical　devices.　©　2024　Higher　Education　Press　Limited　Company.　All　rights　reserved.