Thiamphenicol　(THA)　and　florfenicol　(FLU)　aqueous　solutions　were　irradiated　to　different　doses　by　1　MeV　electron　beams,　and　redox　reactions　of　THA/FLO　and　radicals　of　OH,　e(aq)(-)　and　H-center　dot　were　investigated　under　various　conditions.　The　results　showed　that　at　8　kGy,　the　decomposition　rate　of　THA　and　FLU　was　97.2%　and　98.5%,　respectively.　Quantitative　and　qualitative　analysis　indicated　that　OH　played　a　key　role　in　E-beam　degradation　of　the　THA　and　FLU　in　aqueous　solutions,　and　e(aq)(-)　and　H-center　dot　radicals　could　initiate　the　degradation,　too.　Seven　primary　products　of　the　THA　and　FLU　degradation　were　identified.　These　indicate　that　E-beam　radiation　is　an　effective　method　to　reduce　THA　and　FLU　in　aqueous　solutions.