A　series　of　three-dimensionally　ordered　macroporous　(3DOM)　VMgO　catalysts　were　prepared　by　the　colloidal　crystal　templating　method.　The　obtained　catalysts　were　characterized　by　means　of　BET,　SEM,　TEM,　FT-IR,　XRD　and　H-2-TPR.　The　results　show　that　the　amount　of　vanadium　species　can　have　an　impact　on　the　morphology　of　the　3DOM　VMgO　catalysts,　i.e.　particle　size　and　porous　structure.　The　catalyst　with　32　wt%　V2O5　shows　the　highest　catalytic　performance　with　the　yield　of　propene　amounting　to　11.3%.　Compared　with　the　amorphous　conventional　VMgO,　the　3DOM　structured　catalysts　exhibited　higher　propene　selectivity　due　to　that　the　efficient　diffusion　of　intermediates　and　inhibition　of　consecutive　propene　oxidation.　The　FT-IR,　XRD　and　H-2-TPR　data　confirm　that　isolated　VO4　tetrahedral　groups　are　the　main　promoting　factor　in　the　catalysis.　Further,　the　3DOM　VMgO　catalysts　show　high　stability　in　the　catalysis.