Photocatalysis　is　a　promising　technology　for　removing　micropollutants　in　water.　However,　developing　efficient　and　stable　catalysts　remains　a　challenge.　In　this　work,　a　novel　step-scheme　(S-scheme)　heterojunction　of　WO3/SnIn4S8　(WSI)　was　constructed　through　the　combined　process　of　in　situ　precipitation　with　hydrothermal　synthesis　to　simultaneously　realize　photocatalytic　degradation　of　bisphenol　A(BPA)　and　reduction　of　Cr(VI)　in　contaminated　water.　Results　showed　that　the　WSI　S-scheme　heterojuction　has　a　synergistic　effect　for　the　removal　of　BPA　and　Cr(VI).　An　optimum　case　of　the　WSI-12%　heterojunction　exhibited　the　highest　photocatalytic　efficiency　in　the　degradation　of　BPA　under　visible　light,　which　is　ca.　2.5　and　3.8　times　more　than　the　pure　WO3　and　SIS,　respectively.　The　enhanced　photocatalytic　activity　is　attributed　to　the　formation　of　the　WSI　S-scheme　heterojunctions　which　facilitate　the　spatial　separation　of　charge　carriers　and　preserve　strong　photoredox　ability.　Further,　the　S-scheme　mechanism　of　enhanced　photocatalysis　was　examined　by　the　radical-trapping　experiment　and　ESR,　and　superoxide　and　hydroxyl　radicals　were　determined　to　be　the　major　reactive　oxygen　species　responsible　for　BPA　degradation　and　Cr(VI)　reduction　by　WSI.　This　work　provides　a　novel　strategy　for　tailoring　high-performance　S-scheme　heterojunctions　and　shows　the　promising　application　in　purifying　wastewater　with　complex　pollutants.　©　2023　by　the　authors.