The　transition　of　large-scale　cryogenic　propellant　tanks　from　metal　to　composite　materials　is　the　main　trend　in　the　global　aerospace　industry.　Aiming　to　address　the　challenges　of　achieving　the　manufacturing　of　integrated　and　cost-effective　manufacturing　of　aerospace　cryogenic　composite　tanks　that　cannot　be　realized　through　the　conventional　autoclave　process,　and　those　of　existing　out-of-autoclave　processes　that　are　unable　to　effectively　suppress　defects　under　low-pressure　conditions,　a　vibration　pretreatment　was　innovatively　introduced　into　the　microwave　curing　process　of　composite　materials　in　this　study.　Based　on　a　systematic　analysis　of　the　inhibitory　mechanisms　of　vibration　pretreatment　on　void　formation　and　the　uniform　heating　mechanisms　of　microwaves　in　composite　materials,　the　experimental　results　showed　that　the　compound　curing　process　enabled　the　production　of　components　with　complex　structural　features　under　low-pressure　conditions　while　achieving　equivalent　surface　precision　and　comprehensive　properties,　including　porosity,　interlaminar　shear　strength,　and　cryogenic　permeation　resistance,　as　those　obtained　through　the　standard　0.6　MPa　autoclave　process.　This　holds　great　promise　for　the　application　of　out-of-autoclave　processes　in　the　manufacturing　of　large-scale　aerospace　cryogenic　composite　tanks.　©　2023　by　the　authors.