Membrane　distillation　(MD)　has　been　widely　used　for　resource　recovery　from　high-salinity　wastewater,　due　to　its　superior　technical　merits　of　high　separation　efficiency　and　potential　integration　of　low-grade　heat.　Herein,　a　robust　superhydrophobic　PVDF　membrane　prepared　by　spray-coating　of　fluorinated　silica　nanoparticles　was　employed　to　treat　highly　saline　dye　wastewater　by　MD.　Specifically,　impacts　of　operation　conditions,　including　temperature　difference,　feed　flow-rate,　salinity,　dye　concentration,　and　dye　species,　on　MD　performance　of　the　fabricated　superhydrophobic　PVDF　membrane　were　comprehensively　investigated.　The　increase　of　temperature　difference　and　feed　flow-rate　had　a　positive　effect　on　the　MD　flux　of　the　membrane.　Conversely,　the　rise　in　salinity　and　dye　concentration　induced　an　adverse　impact　on　the　MD　flux.　Furthermore,　the　superhydrophobic　PVDF　membrane　showed　a　strong　robustness　in　treating　complex　streams,　as　demonstrated　by　consistently　stable　MD　flux　using　various　dye/NaCl　mixed　solutions.　Due　to　the　robust　surface　superhydrophobicity,　the　fabricated　PVDF　membrane　exhibited　impressive　antiwetting　and　antifouling　properties　against　highly　saline　dye　wastewater,　consistently　stable　permeation　flux,　and　high　dye/salt　removal　efficiency　(＞99.99%).　Moreover,　the　superhydrophobic　membrane　showed　a　high　water　recovery　(90%)　from　highly　saline　dye　wastewater　with　a　slight　reduction　(13.4%)　in　permeation　flux　during　a　39　h　MD　filtration.　These　results　signify　the　promising　practicability　of　the　fabricated　superhydrophobic　PVDF　membrane　in　sustainable　management　of　highly　saline　dye　wastewater　via　MD.　©　2022　American　Chemical　Society.