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UPLC-MS/MS法研究敌百虫对鱼脑微透析样品中乙酰胆碱和胆碱含量的影响
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采用微透析取样和超高效液相色谱串联质谱(UPLC-MS/MS)相结合,开发了一种定量分析有机磷农药敌百虫对鲫鱼脑部乙酰胆碱(ACh)和胆碱(Ch)影响的方法.探讨了有机磷农药的中毒机制,发现随着敌百虫暴露时间增长,鱼脑中ACh含量显著增加、Ch含量减少,说明有机磷农药抑制了生物体中胆碱酯酶的活性.
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2023,分析试验室
Translated Title
Effects of trichlorfon on the contents of acetylcholine and choline in fish brain microdialysis samples by UPLC-MS/MS method
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WF:perioarticalfxsys202304003
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Chinese
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分析试验室
ISSN: 1000-0720
Year: 2023
Issue: 4
Volume: 42
Page: 442-448
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ESI Highly Cited Papers on the List: 0 Unfold All
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30 Days PV: 3
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