The　lack　of　maintenance　activities　to　prevent　and　reduce　deterioration　and　collapse,　on　a　local　and　global　scale,　is　one　of　the　main　problems　affecting　the　infrastructures.　This　research　focuses　on　the　selection　of　a　rehabilitation　intervention　on　an　R.C.　bridge　by　evaluating　the　sustainability　of　various　alternatives　using　an　innovative　methodology.　Through　multi-criteria　decision　analysis　(e.g.,　AHP,　MIVES　and　TOPSIS),　a　procedural　approach　is　developed　to　evaluate　the　whole　Life　Cycle　Assessment　of　the　maintenance　work　of　a　bridge　column.　Using　environmental,　economic,　social　and　structural　parameters,　the　following　four　different　interventions　on　a　column　of　the　Brabau　Bridge　in　Italy　are　designed,　assessed　and　ranked:　i.　complete　substitution　of　the　pier;　ii.　replacement　of　damaged　longitudinal　bars　by　machined　bars　and　UHPFRC　strengthening;　iii.　longitudinal　and　transverse　wrapping　with　CFRP;　iv.　concrete　jacketing.　The　proposed　methodology　seems　to　be　a　promising　procedure　to　select　the　optimal　rehabilitation　technique　considering　the　sustainability-related　issues.　©　2023,　The　Author(s),　under　exclusive　license　to　Springer　Nature　Switzerland　AG.