This　paper　presents　an　extensive　experimental　characterization　of　Pakistani　brick　masonry　walls　under　different　brick　and　mortar　typologies.　The　investigation　involves　separate　tests　on　bricks　and　mortar　and　compression　tests　on　entire　masonry　assemblies　with　three　load　directions:　horizontal,　vertical　and　diagonal.　Additionally,　12　triplet　masonry　samples　were　tested　to　assess　the　friction　coefficient　and　cohesion　between　bricks　and　mortar　layers.　The　experimental　results　are　used　to　calibrate　an　empirical　equation　for　the　masonry　strength　prediction.　Based　on　existing　literature,　the　strength　depends　on　the　slenderness　ratio,　the　width–thickness　ratio,　and　the　strength　of　brick　and　mortar.　The　proposed　equation　also　considers　the　wall　width-to-thickness　ratio,　which　is　seldom　considered　in　past　studies.　Additional　empirical　relationships　have　been　derived　between　parameters　such　as　the　vertical　and　horizontal　masonry　strength,　the　Young＇s　and　shear　moduli.　A　comprehensive　comparative　study　validates　the　accuracy　of　the　proposed　equation,　showing　a　good　accuracy　compared　to　a　set　of　33　experimental　tests　carried　out　in　the　last　40　years.　The　proposed　equation　can　be　used　to　predict　Pakistani　brick　walls　and　other　brick　masonry　typologies　with　an　average　absolute　error　equal　to　nearly　10%.　©　2023　Elsevier　Ltd