Pressure　leaching　is　a　promising　technology　to　process　the　copper-cobalt　sulfide.　In　this　work,　the　behaviors　of　copper-cobalt　sulfide　flotation　concentrates　received　from　Congo　during　pressure　leaching　were　investigated　for　varying　temperatures,　acidity,　leaching　time,　solid　to　liquid　ratio,　and　oxygen　partial　pressure.　A　one　factor　at　a　time　method　was　implemented　to　obtain　the　optimal　operating　condition,　XRD,　EDS,　ICP-OES　methods　were　used　to　examine　the　chemical　composition,　state　as　well　as　metal　content　of　samples.　It　is　found　that　the　recovery　percentage　for　copper　and　cobalt　can　reach　99　%　and　98　%　under　temperature　190　°C,　oxygen　partial　pressure　6　atm,　leaching　time　2　h,　liquid　to　solid　ratio　5:1,　initial　acidity　0　g/L.　The　kinetics　study　shows　that　the　chemical　reaction　is　the　control　step　during　pressure　leaching　of　copper　and　cobalt.　The　coating　of　hematite　on　the　mineral　surface　is　the　main　reason　for　the　incomplete　leaching　of　copper　and　cobalt.　©　2022　Elsevier　B.V.