Soil-structure　interaction　effect　(SSI　effect)　under　the　long-period　ground　motion　affects　the　dynamic　characteristics　of　the　base　isolation　structure.Long-period　ground　motion　makes　such　structures　as　base　isolation　structure　have　strong　seismic　response,　which　may　be　greater　when　SSI　effect　is　considered.　Therefore,　the　shaking　table　test　of　isolation　structure　and　numerical　simulation　research　were　carried　out,　and　the　impact　of　long-period　ground　motion　and　SSI　effect　on　the　dynamic　response　of　the　base　isolation　structure　were　explored.　Damping　and　limit　protection　effects　of　composite　isolation　structure　with　additional　viscous　dampers　on　the　isolation　layer　are　verified.　The　results　show　that　the　SSI　effect　will　increase　the　inter　story　displacement　response　of　floors　above　the　isolation　layer;　isolation　layer　displacement　considering　SSI　effect　and　upper　structure　interlayer　drift　ratio　will　exceed　limit　under　near-field　impulse　large　earthquake;　composite　seismic　isolation　scheme　can　avoid　structural　damage　caused　by　displacement　overrun　and　improve　damping　effect.It　is　suggested　that　the　impact　of　SSI　effect　should　be　considered　when　using　base　isolation　technology　in　practical　engineering,　with　independent　working　condition　analysis　of　near-field　pulse　ground　motion　and　compound　seismic　isolation　design.　©　2022,　The　Editorial　Board　of　Journal　of　Basic　Science　and　Engineering.　All　right　reserved.