Recently,　the　CO2　hydrate　as　cold　storage　medium　draws　much　attention　and　some　thermodynamic　promoters　are　proposed　to　moderate　its　hydrate　formation　condition　for　reducing　energy　consumption.　In　this　study,　the　hydrate　phase　equilibrium　conditions　of　CO2　in　the　presence　of　tetrahydrofuran　(THF),　cyclopentane　(CP),　tetrabutylammonium　bromide　(TBAB)　were　measured　with　the　isochoric　pressure　searching　method.　The　hydrate　dissociation　enthalpies　were　calculated　with　Clausius-Clapeyron　equation　base　on　the　measured　data　sets.　The　results　showed　that　the　hydrate　phase　equilibrium　temperature　of　CO2　in　the　aqueous　solution　containing　promoters　increased　at　least　12　K　at　1.5　MPa　compared　to　that　of　CO2　in　the　pure　water　system.　The　hydrate　dissociation　enthalpies　of　(CO2+CP+H2O),　(CO2+THF+H2O),　(CO2+TBAB+H2O)　reached　136.16,　147.07,　205.75　kJ.mol−1,　respectively,　which　significantly　increased　than　that　of　(CO2+H2O)　(64.93　kJ.mol−1).　A　thermodynamic　framework　was　proposed　to　prediction　the　hydrate　phase　equilibria　of　CO2　in　the　presence　of　promoters.　The　Chen-Guo　(C-G)　model　was　used　to　calculate　the　fugacity　of　hydrate　phase,　the　NRTL　and　developed　PMZH　models　were　used　to　calculate　the　activity　of　liquid　phase.　The　CO2　solubility　was　calculated　by　the　modified　Henry＇s　law,　and　the　effect　of　volatile　component　in　aqueous　phase　on　the　composition　of　gas　phase　was　investigated.　The　predictions　of　our　proposed　model　agree　well　with　the　measured　data　in　this　work　as　well　as　literature　values.　©　2022