Massive　bleeding　and　wound　infection　are　the　major　problems　often　observed　during　severe　trauma,　and　achieving　rapid　hemostasis　in　cases　of　high-dose　bleeding　in　arteries　and　viscera　remains　an　acute　clinical　demand.　Herein,　a　mussel-　and　barnacle　cement　proteins-inspired　dual-bionic　hydrogel　is　first　proposed.　Benefiting　from　abundant　phenolic　hydroxyl　groups,　a　tough　dissipative　matrix,　removal　of　interfacial　water,　as　well　as　dynamic　redox　balance　of　phenol-quinone,　the　multinetwork　hydrogel　achieves　repeatable　robust　wet-tissue　adhesiveness　(151.40 ± 1.50 kPa),　a　fast　multimodal　self-healing　ability,　and　excellent　antibacterial　property　against　both　Gram-positive/negative　bacteria.　For　rabbit/pig　models　of　cardiac　penetration　holes　and　femoral　artery　injuries,　the　dual-bionic　bioadhesive　shows　better　hemostatic　efficiency　than　commercial　gauze　due　to　the　synergistic　effect　of　strong　wound　sealing　capability,　excellent　red　blood　cell　capturing　property,　and　activation　of　hemostatic　barrier　membrane.　More　interestingly,　the　hydrogel　combined　with　commercial　hemostatic　sponge　presents　accelerated　wound　healing　as　well　as　great　potential　for　treating　deep-wound　hemorrhage　in　a　battlefield　environment.　Overall,　owing　to　these　unique　advantages,　the　novel　tissue-adhesive　hemostat　opens　up　a　new　avenue　to　rapid　sealing　hemostasis　and　wound　healing　applications.　©　2022　Wiley-VCH　GmbH.