Microplastics　(MPs),　tiny　particles　broken　down　from　larger　pieces　of　plastics,　have　accumulated　everywhere　on　the　earth.　As　an　inert　carbon　stream　in　aquatic　environment,　they　have　been　reported　as　carriers　for　heavy　metals　and　exhibit　diverse　interactive　effects.　However,　these　interactions　are　still　poorly　understood,　especially　mechanisms　driving　these　interactions　and　how　they　pose　risks　on　living　organisms.　In　this　mini　review,　a　bibliometric　analysis　in　this　field　was　conducted　and　then　the　mechanisms　driving　these　interactions　were　examined,　especially　emphasizing　the　important　roles　of　microorganisms　on　the　interactions.　Their　combined　toxic　effects　and　the　potential　hazards　to　human　health　were　also　discussed.　Finally,　the　future　research　directions　in　this　field　were　suggested.　This　review　summarized　the　recent　research　progress　in　this　field　and　highlighted　the　essential　roles　of　the　microbes　on　the　interactions　between　MPs　and　heavy　metals　with　the　hope　to　promote　more　studies　to　unveil　action　mechanisms　and　reduce/eliminate　the　risks　associated　with　MP　presence.