Abstract:
Chemotherapy-induced myelosuppression and aplastic anemia are bone marrow failure syndromes characterized by peripheral pancytopenia and marrow hypoplasia.Few good therapeutics have been developed to solve the problems.We have identified a novel peptide(PP),derived from serum albumin,with a potent activity to stimulate hematopoietic cells proliferation.Assay of proliferation in vitro was carried out with human haematopoietic stem cells (CD34+)and bone marrow nucleated cells from healthy volunteers and aplastic anemia patients''bone marrow (donors), respectively.
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Reprint 's Address:
Source :
Year: 2008
Page: 233-234
Language: Chinese
Affiliated Colleges: