A　sliding　mode-neural　network　scheme　based　on　hybrid　trajectory　was　proposed　to　track　the　hybrid　trajectory　of　a　space　flexible　manipulator,　meanwhile,　the　flexible　vibration　can　be　suppressed.　In　order　to　actively　suppress　the　flexible　vibration,　the　hybrid　trajectory　for　sliding　mode-neural　network　controller　was　generated　by　using　the　virtual　control　force　concept,　which　reflected　the　flexible　variables　as　well　as　the　rigid　desired　trajectories.　Based　on　the　hybrid　trajectory,　the　new　sliding　mode-neural　network　control　can　be　designed.　Simulations　results　confirm　that　the　proposed　control　scheme　can　dominates　the　trajectory　tracking　the　coordinated　motion　and　actively　suppress　the　vibrations　in　the　presence　of　parameter　uncertainty.