In　this　paper,　the　research　progress　on　organic/inorganic　bone　regeneration　materials　in　the　last　5　years　is　reviewed.　According　to　the　different　composition　of　materials,　the　advantages　and　disadvantages　of　each　material　on　the　biocompatability,　biodegradability,　bioactivity　and　mechanical　property　are　discussed　respectively.　In　addition,　the　problems　in　bone　regeneration　field　are　analyzed　and　the　prospect　of　artificial　bone　substitute　materials　is　made.