In　the　information　age,　the　pace　of　technological　upgrading　is　faster.　Industry-University-Institute　Cooperation　is　becoming　a　new　way　of　knowledge　production　and　technology　transfer　as　an　important　component　of　national　innovation　systems　form.　How　to　achieve　a　better　research　cooperation　innovation,　reduce　the　intellectual　property　risks　which　universities,　research　institutions　face　has　become　the　focus　of　academic　attention.　This　paper　builds　a　relational　embedding　model　based　on　intermediary　variable　approach　which　used　to　control　the　risks　in　Industry-University-Institute　Cooperation;　Furthermore,　this　paper　provide　a　structural　equation　model　to　evaluate　the　new　approach.　©　2011　IEEE.