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author:

Chen, X. (Chen, X..) [1] | Ye, H. (Ye, H..) [2] | Wang, W. (Wang, W..) [3] | Qiu, B. (Qiu, B..) [4] | Lin, Z. (Lin, Z..) [5] | Chen, G. (Chen, G..) [6]

Indexed by:

Scopus

Abstract:

Glucose oxidase(GOD) was encapsulated in the Graphene/Nafion film modified glassy carbon electrode(GCE) and used as an ECL sensor for glucose. The GOD retains its bioactivity after being immobilized into the composite film. The sensor gives a linear response for glucose in the range of 2.0×10-6-1.0×10-4 mol/L with a detection limit of 1.0×10-6 mol/L. The sensor showed good stability, the RSD for continuous scanning for 5.0×10-5 mol/L glucose was 4.21% (n=5). After being stored in 0.05 mol/L pH 7.4 PBS in 48C for two weeks, the modified electrode maintains 80% of its initial activity. The glucose sensor provides new opportunity for clinical diagnosis applications. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Keyword:

Biosensors; Electrochemiluminescence; Glucose; Graphene

Community:

  • [ 1 ] [Chen, X.]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
  • [ 2 ] [Ye, H.]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
  • [ 3 ] [Wang, W.]Department of Orthopedics, Fuzhou General Hospital of Nanjing Military Command, Fuzhou 350025, China
  • [ 4 ] [Qiu, B.]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
  • [ 5 ] [Lin, Z.]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China
  • [ 6 ] [Chen, G.]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China

Reprint 's Address:

  • [Lin, Z.]Ministry of Education Key Laboratory of Analysis and Detection for Food Safety, Fujian Provincial Key Laboratory of Analysis and Detection for Food Safety, Department of Chemistry, Fuzhou University, Fuzhou, Fujian, 350002, China

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Source :

Electroanalysis

ISSN: 1040-0397

Year: 2010

Issue: 20

Volume: 22

Page: 2347-2352

2 . 7 2 1

JCR@2010

2 . 7 0 0

JCR@2023

JCR Journal Grade:2

CAS Journal Grade:3

Cited Count:

WoS CC Cited Count:

SCOPUS Cited Count: 52

ESI Highly Cited Papers on the List: 0 Unfold All

WanFang Cited Count:

Chinese Cited Count:

30 Days PV: 0

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