Development of a concise synthetic approach to access oroxin A - Details

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Abstract：

A　novel　environment-friendly　method　to　access　bioactive　oroxin　A　through　a　one-pot/two-step　process　from　naturally　abundant　and　inexpensive　baicalin　is　described.　The　procedure　presented　here　has　several　advantages　including　clean,　one-pot,　synthetic　ease,　and　large-scale　feasibility.　This　work　also　provides　a　model　strategy　for　rapid　and　diverse　access　to　natural　molecules　sharing　the　common　skeleton　of　this　family.　©　2014　the　Partner　Organisations.

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[ 1 ] [Chen, H.]College of Chemistry, Fuzhou University, Fuzhou Fujian, 350108, China
[ 2 ] [Chen, H.]Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77555, United States
[ 3 ] [He, G.]College of Chemistry, Fuzhou University, Fuzhou Fujian, 350108, China
[ 4 ] [Li, C.]College of Chemistry, Fuzhou University, Fuzhou Fujian, 350108, China
[ 5 ] [Dong, L.]College of Chemistry, Fuzhou University, Fuzhou Fujian, 350108, China
[ 6 ] [Xie, X.]College of Chemistry, Fuzhou University, Fuzhou Fujian, 350108, China
[ 7 ] [Wu, J.]College of Chemistry, Fuzhou University, Fuzhou Fujian, 350108, China
[ 8 ] [Gao, Y.]College of Chemistry, Fuzhou University, Fuzhou Fujian, 350108, China
[ 9 ] [Zhou, J.]Chemical Biology Program, Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, TX 77555, United States

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[Chen, H.]College of Chemistry, Fuzhou UniversityChina

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RSC Advances

ISSN： 2046-2069

Year： 2014

Issue： 85

Volume： 4

Page： 45151-45154

3 . 8 4

JCR@2014

3 . 9 0 0

JCR@2023

ESI HC Threshold：268

JCR Journal Grade：1

CAS Journal Grade：3

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SCOPUS Cited Count： 6

ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 4

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