A　new　approach　to　the　synthesis　of　fluorinated　biaryl　compounds　from　easily　available　starting　materials　is　described.　This　protocol　is　based　on　the　direct　palladium-catalyzed　desulfitative　cross-coupling　of　polyfluoroarenes　with　various　arylsulfinate　salts　via　CH　bond　activation,　accelerated　by　trace　amount　of　water.　The　method　allows　the　synthesis　of　various　fluorinated　biaryl　products　in　moderate　to　good　yields,　and　tolerated　a　variety　of　functional　groups,　including　alkyl,　phenyl,　methoxy,　fluoro,　and　chloro　groups.　©　2014　Elsevier　B.V.