A silicon(IV) phthalocyanine-folate conjugate as an efficient photosensitizer - Details

author：

Zheng, Y.-W. (Zheng, Y.-W..) ^[1] | Chen, S.-F. (Chen, S.-F..) ^[2] | Zheng, B.-Y. (Zheng, B.-Y..) ^[3] | Ke, M.-R. (Ke, M.-R..) ^[4] | Huang, J.-D. (Huang, J.-D..) ^[5]

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Abstract：

The　novel　silicon(IV)　phthalocyanine　axially　conjugated　with　two　molecules　of　folic　acid　has　been　prepared　and　characterized.　Its　photophysical　and　photochemical　properties　and　photodynamic　activities　have　also　been　evaluated.　This　conjugate　shows　high　photodynamic　activities　toward　HeLa　human　cervical　carcinoma　cells　(IC50　=　0.071　μM);　this　activity　is　slightly　higher　than　that　of　HepG2　human　hepatocellular　carcinoma　cells　(IC50　=　0.118　μM).　©　2014　The　Chemical　Society　of　Japan.

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[ 1 ] [Zheng, Y.-W.]College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 2 ] [Chen, S.-F.]College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 3 ] [Zheng, B.-Y.]College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 4 ] [Ke, M.-R.]College of Chemistry, Fuzhou University, Fuzhou, 350108, China
[ 5 ] [Huang, J.-D.]College of Chemistry, Fuzhou University, Fuzhou, 350108, China

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[Huang, J.-D.]College of Chemistry, Fuzhou UniversityChina

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Source ：

Chemistry Letters

ISSN： 0366-7022

Year： 2014

Issue： 11

Volume： 43

Page： 1701-1703

1 . 2 3

JCR@2014

1 . 4 0 0

JCR@2023

ESI HC Threshold：268

JCR Journal Grade：3

CAS Journal Grade：4

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SCOPUS Cited Count： 17

ESI Highly Cited Papers on the List： 0 Unfold All

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30 Days PV： 2

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